Treatment of high-energy lower extremity trauma is explained by the Orthopaedic Trauma Association Open Fracture Classification.

Julie Agel, Lisa Reider, Saam Morshed, Anthony R Carlini, Renan C Castillo, Raymond A Pensy, Jason J Yoo, Michael J Bosse
{"title":"Treatment of high-energy lower extremity trauma is explained by the Orthopaedic Trauma Association Open Fracture Classification.","authors":"Julie Agel, Lisa Reider, Saam Morshed, Anthony R Carlini, Renan C Castillo, Raymond A Pensy, Jason J Yoo, Michael J Bosse","doi":"10.1097/OI9.0000000000000469","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To examine the association of Orthopaedic Trauma Association Open Fracture Classification (AO FC-OFC) designation for a specific high-energy lower extremity fracture with the need for 3 or more surgeries, soft -tissue closure with a flap, or amputation.</p><p><strong>Design: </strong>Secondary analysis of multicenter prospective observational study.</p><p><strong>Setting: </strong>Thirty-two Level 1 trauma centers.</p><p><strong>Patient/participants: </strong>Adult patients admitted from July 2012 to October 2015 with open pilon, ankle, talus, calcaneus, foot crush, or blast injuries.</p><p><strong>Main outcome measurements: </strong>Multivariable regression analyses examined the association between the OTA-FC (contamination, bone loss, muscle, skin and arterial injury) with 3 or more trips to the OR before definitive fixation, soft-tissue closure with a flap, and amputation within 18 months of injury.</p><p><strong>Results: </strong>A total of 447 patients comprised the study population. In adjusted models, embedded contamination [odds ratio (OR) = 3.0, 95% confidence interval (CI): 1.54-5.99], functional muscle loss (OR = 2.6, 95% CI: 1.60-4.23), skin that cannot be approximated (OR = 10.0, 95% CI: 5.02-19.79), and degloving (OR = 5.9, 95% CI: 2.94-11.61) were significantly associated with 3+ OR trips. Embedded contamination (OR = 2.2, 95% CI: 1.00-4.86), skin that cannot be approximated (OR = 23.8, 95% CI: 11.73-48.12), and degloving (OR = 12.4, 95% CI: 5.87-26.05) were significantly associated with soft tissue closure with a flap. Dead muscle (OR = 12.9, 95% CI: 4.78-34.89), arterial injury with ischemia (OR = 12.0, 95% CI: 3.22-44.27), skin that cannot be approximated (OR = 2.4, 95% CI: 1.03-5.37), and degloving (OR = 3.0, 95% CI: 1.25-6.98) were significantly associated with amputation.</p><p><strong>Conclusions: </strong>The OTA-FC variables that were most important for predicting treatment intervention varied. The severity of skin injury was associated with all outcomes.</p>","PeriodicalId":74381,"journal":{"name":"OTA international : the open access journal of orthopaedic trauma","volume":"9 1","pages":"e469"},"PeriodicalIF":0.0000,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12956240/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"OTA international : the open access journal of orthopaedic trauma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/OI9.0000000000000469","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/3/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives: To examine the association of Orthopaedic Trauma Association Open Fracture Classification (AO FC-OFC) designation for a specific high-energy lower extremity fracture with the need for 3 or more surgeries, soft -tissue closure with a flap, or amputation.

Design: Secondary analysis of multicenter prospective observational study.

Setting: Thirty-two Level 1 trauma centers.

Patient/participants: Adult patients admitted from July 2012 to October 2015 with open pilon, ankle, talus, calcaneus, foot crush, or blast injuries.

Main outcome measurements: Multivariable regression analyses examined the association between the OTA-FC (contamination, bone loss, muscle, skin and arterial injury) with 3 or more trips to the OR before definitive fixation, soft-tissue closure with a flap, and amputation within 18 months of injury.

Results: A total of 447 patients comprised the study population. In adjusted models, embedded contamination [odds ratio (OR) = 3.0, 95% confidence interval (CI): 1.54-5.99], functional muscle loss (OR = 2.6, 95% CI: 1.60-4.23), skin that cannot be approximated (OR = 10.0, 95% CI: 5.02-19.79), and degloving (OR = 5.9, 95% CI: 2.94-11.61) were significantly associated with 3+ OR trips. Embedded contamination (OR = 2.2, 95% CI: 1.00-4.86), skin that cannot be approximated (OR = 23.8, 95% CI: 11.73-48.12), and degloving (OR = 12.4, 95% CI: 5.87-26.05) were significantly associated with soft tissue closure with a flap. Dead muscle (OR = 12.9, 95% CI: 4.78-34.89), arterial injury with ischemia (OR = 12.0, 95% CI: 3.22-44.27), skin that cannot be approximated (OR = 2.4, 95% CI: 1.03-5.37), and degloving (OR = 3.0, 95% CI: 1.25-6.98) were significantly associated with amputation.

Conclusions: The OTA-FC variables that were most important for predicting treatment intervention varied. The severity of skin injury was associated with all outcomes.

Abstract Image

高能下肢创伤的治疗由骨科创伤协会开放性骨折分类解释。
目的:探讨骨科创伤协会开放性骨折分类(aofc - ofc)指定与需要3次或更多手术、皮瓣闭合软组织或截肢的特定高能下肢骨折的关系。设计:多中心前瞻性观察研究的二次分析。地点:32个一级创伤中心。患者/参与者:2012年7月至2015年10月住院的成人患者,伴有开腹、踝关节、距骨、跟骨、足部挤压或爆炸伤。主要结果测量:多变量回归分析检查了OTA-FC(污染、骨质流失、肌肉、皮肤和动脉损伤)与最终固定前3次或更多次去手术室、皮瓣闭合软组织和损伤后18个月内截肢之间的关系。结果:共有447名患者组成了研究人群。在调整后的模型中,嵌入污染[比值比(OR) = 3.0, 95%可信区间(CI): 1.54-5.99]、功能性肌肉损失(OR = 2.6, 95% CI: 1.60-4.23)、无法近似的皮肤(OR = 10.0, 95% CI: 5.02-19.79)和脱手套(OR = 5.9, 95% CI: 2.94-11.61)与3+ OR绊倒显著相关。嵌入污染(OR = 2.2, 95% CI: 1.00-4.86)、无法接近的皮肤(OR = 23.8, 95% CI: 11.73-48.12)和脱手套(OR = 12.4, 95% CI: 5.87-26.05)与皮瓣闭合软组织显著相关。死肌(OR = 12.9, 95% CI: 4.78-34.89)、动脉缺血损伤(OR = 12.0, 95% CI: 3.22-44.27)、不能近似的皮肤(OR = 2.4, 95% CI: 1.03-5.37)和脱手套(OR = 3.0, 95% CI: 1.25-6.98)与截肢显著相关。结论:预测治疗干预最重要的OTA-FC变量各不相同。皮肤损伤的严重程度与所有结果相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
审稿时长
4 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书