NATURAL HISTORY OF THE GASTROJEJUNAL ANASTOMOSIS IN PATIENTS UNDERGOING ROUX-EN-Y GASTRIC BYPASS.

Q2 Medicine

Arquivos de Gastroenterologia Pub Date : 2026-03-02 eCollection Date: 2026-01-01 DOI:10.1590/S0004-2803.24612025-065

Gustavo Henrique Xavier Caseiro, Vitor Ottoboni Brunaldi, Maisa Buissa, Roberto Luiz Kaiser-Junior, Carolina Colombelli Pacca, Luiz Gustavo de Quadros

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引用次数: 0

Abstract

Background: Obesity is considered a global epidemic and has shown a progressive increase in recent decades. Bariatric surgery, such as Roux-en-Y gastric bypass (RYGB), is the most effective sustainable weight loss option. However, weight regain is one of the challenges facing patients and is attributed to several factors, including dilatation of the gastrojejunal anastomosis (GJA).

Objectives: The central objective of this study is to correlate the influence of time on GJA widening in patients undergoing RYGB over a 7-year period.

Methods: Prospective and longitudinal study conducted over 7 years in patients undergoing RYGB. Surgical and endoscopic procedures were performed in a medium hospital in the same city. Weight, body mass index (BMI) and GJA size were assessed at intervals of 2, 6, 12, 24, 30, 48, 60, and 72 months after the surgical procedure.

Results: The highest mean value in the distribution of anastomosis diameter was 20±2.27 mm at 72 months after surgery. The lowest mean value was 10.2±1.70 mm at 2 months after surgery. The analysis showed that there is a significant effect of time on anastomosis diameter, with statistically significant differences in the mean value between 2, 6, 12, 24, 60, and 72 months after surgery (F(1,724,5,172)=9.555, P<0.05).

Conclusion: Multiple comparative analysis showed that there are statistically significant differences between the mean lengths of anastomosis across the times studied, with a greater influence of the time factor 24 months after surgery.

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roux-en-y胃旁路术患者胃空肠吻合的自然历史。

背景：肥胖被认为是一种全球性的流行病，并且在近几十年来呈现出逐渐增加的趋势。减肥手术，如Roux-en-Y胃旁路手术（RYGB），是最有效的可持续减肥选择。然而，体重反弹是患者面临的挑战之一，并归因于几个因素，包括胃空肠吻合口扩张（GJA）。目的：本研究的中心目的是在7年的时间内，研究时间对RYGB患者GJA扩大的影响。方法：对RYGB患者进行为期7年的前瞻性和纵向研究。手术和内窥镜检查在同一城市的一家中型医院进行。在手术后2、6、12、24、30、48、60和72个月对体重、体重指数（BMI）和GJA大小进行评估。结果：术后72个月吻合口直径分布平均值最高，为20±2.27 mm。术后2个月最低平均值为10.2±1.70 mm。分析显示时间因素对吻合口直径有显著影响，术后2、6、12、24、60、72个月的吻合口直径均值差异有统计学意义（F(1724, 5172)=9.555, p）结论：多次比较分析显示，各时间段吻合口平均长度差异有统计学意义，且术后24个月时间因素影响较大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arquivos de Gastroenterologia Medicine-Gastroenterology

CiteScore

2.00

自引率

0.00%

发文量

109

审稿时长

9 weeks

期刊介绍： The journal Arquivos de Gastroenterologia (Archives of Gastroenterology), a quarterly journal, is the Official Publication of the Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia IBEPEGE (Brazilian Institute for Studies and Research in Gastroenterology), Colégio Brasileiro de Cirurgia Digestiva - CBCD (Brazilian College of Digestive Surgery) and of the Sociedade Brasileira de Motilidade Digestiva - SBMD (Brazilian Digestive Motility Society). It is dedicated to the publishing of scientific papers by national and foreign researchers who are in agreement with the aim of the journal as well as with its editorial policies.