Study of the printability and rheological behavior of inks formulated with collagen- polycaprolactone-chitosan

IF 2.4 4区工程技术 Q2 MECHANICS

Korea-Australia Rheology Journal Pub Date : 2026-01-12 DOI:10.1007/s13367-025-00148-y

Angela Miscli Rangel-Garcia, Luis Medina-Torres, Octavio Manero, Marco Antonio Álvarez-Pérez, María Cristina Piña-Barba

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引用次数: 0

Abstract

The development of inks for use in 3D printing remains a significant challenge in the field of tissue engineering. In this study, the dimensionless printability factor is calculated by comparing printed images with the desired design, resulting in a value of 0.87 ± 0.11 for ink with the lowest polycaprolactone (PCL) content. A filament collapse test was conducted to ascertain the grid pore size, with results attained within the range of 0.60 to 1 mm. The rheological behavior of inks formulated with collagen (Col), polycaprolactone (PCL) and chitosan (Chi) exhibit shear-thinning viscosity, and decreasing rheological properties with increasing temperature. The storage (G′) and loss (G′′) moduli increase with increasing angular frequency. Results reveal that increasing polymer concentration improves printability and rheological properties of the Col: PCL: Chi inks, allowing the printing of scaffolds with regulated properties leading to important applications in tissue engineering.

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胶原-聚己内酯-壳聚糖配制油墨的印刷性和流变性研究

用于3D打印的油墨的开发仍然是组织工程领域的一个重大挑战。在本研究中，通过将打印图像与期望设计进行比较来计算无量纲印刷适性因子，得到聚己内酯（PCL）含量最低的油墨的值为0.87±0.11。进行了细丝坍塌试验，以确定网格孔径，结果在0.60至1 mm范围内。由胶原蛋白（Col）、聚己内酯（PCL）和壳聚糖（Chi）配制的油墨的流变性能表现为粘度剪切变薄，随温度升高而降低。存储模量（G′）和损耗模量（G′）随角频率的增加而增加。结果表明，增加聚合物浓度可以改善Col: PCL: Chi油墨的打印性能和流变性能，从而可以打印出具有调节性能的支架，从而在组织工程中具有重要的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Korea-Australia Rheology Journal 工程技术-高分子科学

CiteScore

2.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Korea-Australia Rheology Journal is devoted to fundamental and applied research with immediate or potential value in rheology, covering the science of the deformation and flow of materials. Emphases are placed on experimental and numerical advances in the areas of complex fluids. The journal offers insight into characterization and understanding of technologically important materials with a wide range of practical applications.