Robust fine-grained echocardiographic view classification with supervised contrastive learning

IF 14 1区 医学 Q1 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE
Medical image analysis Pub Date : 2026-05-01 Epub Date: 2026-02-26 DOI:10.1016/j.media.2026.104006
Preshen Naidoo , Patricia Fernandes , Nasim Dadashi Serej , Catherine C Stowell , Charlotte H Manisty , Darrel P Francis , Massoud Zolgharni
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引用次数: 0

Abstract

Accurate classification of echocardiographic views is fundamental for automated cardiac analysis. However, clinical practice relies on a large, heterogeneous set of fine-grained acquisitions that introduce substantial inter-observer variability. Existing studies have primarily focused on limited view sets, often collapsing specialised views into broad categories, which limits their clinical relevance. We address this limitation by introducing TTE47, the first publicly available benchmark comprising 47 clinically meaningful views annotated independently by three experts. This dataset enables the rigorous quantification of inter-observer agreement and establishes a foundation for reproducible, clinically relevant evaluation. To tackle the dual challenges of subtle inter-class distinctions and structured label variability, we propose a novel supervised contrastive learning framework incorporating a tailored loss function. Our method outperforms cross-entropy and standard supervised contrastive baselines, achieving leading performance among evaluated methods on TTE47 and surpassing prior work on TMED-2 without dataset-specific pretraining, using a model pretrained on TTE47. Beyond accuracy, we introduce clustering-based metrics, Detection Rate and Label Recovery Precision, that measure semantic coherence and the model’s ability to resist annotation variability. Results show that the learned feature space aligns more strongly with underlying anatomical structure than with any single annotator’s style, enabling resilience to label shifts and maintaining robustness comparable to human-level disagreement. By integrating multi-expert evaluation, robust representation learning, and interpretable feature-space analysis, this work establishes a scalable and clinically relevant framework for fine-grained echo view classification. Our findings highlight the potential of contrastive pretraining to standardise interpretation, mitigate subjectivity, and enhance the reliability of AI-assisted echocardiography in diverse clinical settings.
鲁棒细粒度超声心动图图像分类与监督对比学习
超声心动图图像的准确分类是自动心脏分析的基础。然而,临床实践依赖于大量异构的细粒度采集,这些采集会引入大量的观察者之间的差异。现有的研究主要集中在有限的视图集上,经常将专门的视图分解为广泛的类别,这限制了它们的临床相关性。我们通过引入TTE47来解决这一限制,TTE47是第一个公开可用的基准,由三位专家独立注释的47个临床有意义的观点组成。该数据集能够严格量化观察者之间的一致性,并为可重复的临床相关评估奠定基础。为了解决微妙的类间差异和结构化标签可变性的双重挑战,我们提出了一种包含定制损失函数的新型监督对比学习框架。我们的方法优于交叉熵和标准监督对比基线,在TTE47上的评估方法中取得领先的性能,并且超越了之前在TMED-2上的工作,而不需要针对数据集进行预训练,使用在TTE47上预训练的模型。除了准确性之外,我们还引入了基于聚类的度量,检测率和标签恢复精度,用于测量语义一致性和模型抵抗注释可变性的能力。结果表明,与任何单一注释者的风格相比,学习到的特征空间与潜在解剖结构的一致性更强,从而实现了标记移位的弹性,并保持了与人类水平差异相当的鲁棒性。通过整合多专家评估、稳健的表征学习和可解释的特征空间分析,本研究建立了一个可扩展的、与临床相关的细粒度回声视图分类框架。我们的研究结果强调了对比预训练在标准化解释、减轻主观性和提高人工智能辅助超声心动图在不同临床环境中的可靠性方面的潜力。
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来源期刊
Medical image analysis
Medical image analysis 工程技术-工程:生物医学
CiteScore
22.10
自引率
6.40%
发文量
309
审稿时长
6.6 months
期刊介绍: Medical Image Analysis serves as a platform for sharing new research findings in the realm of medical and biological image analysis, with a focus on applications of computer vision, virtual reality, and robotics to biomedical imaging challenges. The journal prioritizes the publication of high-quality, original papers contributing to the fundamental science of processing, analyzing, and utilizing medical and biological images. It welcomes approaches utilizing biomedical image datasets across all spatial scales, from molecular/cellular imaging to tissue/organ imaging.
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