Effect of HPC Incorporation on Structures and Properties of PVA Electrospun Fiber Membrane

IF 3.6 4区工程技术 Q2 ENGINEERING, CHEMICAL

Polymer Engineering and Science Pub Date : 2025-08-12 DOI:10.1002/pen.70096

Xihao Yang, Xiuling Lin, Shuo Wang, Yong Chen, Xiangyu Dai

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引用次数: 0

Abstract

ABSTRACT The selection of appropriate materials for adjusting the properties of polyvinyl alcohol (PVA) electrospun fiber membrane is an essential objective. In this study, a novel PVA/hydroxypropyl cellulose (PVA/HPC) composite fiber membrane was fabricated through electrospinning technology. The water‐soluble HPC served as an additive to modify the structures and properties of the PVA electrospun fiber membrane. The electrospinning process was optimized with an 8% PVA solution containing different contents of HPC additive, achieving continuous fiber formation at 20 kV applied voltage with a 16 cm collector distance, which significantly improved the spinnability of PVA solutions. The addition of HPC can improve the mechanical properties of the PVA fiber membrane. The PVA/HPC fiber membrane displayed an ideal capacity for sustained drug release and exhibited significant antibacterial activity. The P8H1.5 (PVA/HPC was 8%/1.5%) fibers, which were uniform and defect‐free, demonstrated the best release effect and antibacterial activity. These results suggested that HPC is an ideal material for improving the properties of the PVA electrospun fiber membrane and that the PVA/HPC fiber membrane could be a potential antibacterial and anti‐inflammatory material for medical applications.

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HPC掺入对PVA静电纺丝纤维膜结构和性能的影响

选择合适的材料来调节聚乙烯醇（PVA）静电纺丝纤维膜的性能是一个重要的目标。采用静电纺丝技术制备了新型PVA/羟丙基纤维素（PVA/HPC）复合纤维膜。水溶性HPC作为添加剂对PVA静电纺丝纤维膜的结构和性能进行了改性。以含不同HPC添加剂含量的8% PVA溶液为纺丝剂，对纺丝工艺进行了优化，在20 kV外加电压、16 cm集电极距离下实现了连续成纤维，显著提高了PVA溶液的可纺性。HPC的加入可以改善PVA纤维膜的力学性能。PVA/HPC纤维膜具有理想的药物缓释能力和显著的抗菌活性。P8H1.5 （PVA/HPC为8%/1.5%）纤维具有均匀、无缺陷的释放效果和抗菌活性。这些结果表明，HPC是改善PVA静电纺丝纤维膜性能的理想材料，PVA/HPC纤维膜可能是一种潜在的抗菌和抗炎材料。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Polymer Engineering and Science 工程技术-高分子科学

CiteScore

5.40

自引率

18.80%

发文量

329

审稿时长

3.7 months

期刊介绍： For more than 30 years, Polymer Engineering & Science has been one of the most highly regarded journals in the field, serving as a forum for authors of treatises on the cutting edge of polymer science and technology. The importance of PE&S is underscored by the frequent rate at which its articles are cited, especially by other publications - literally thousand of times a year. Engineers, researchers, technicians, and academicians worldwide are looking to PE&S for the valuable information they need. There are special issues compiled by distinguished guest editors. These contain proceedings of symposia on such diverse topics as polyblends, mechanics of plastics and polymer welding.