The Combined Double-Orifice and Single-Patch Technique for Partial Atrioventricular Septal Defect in Adults: A Novel Strategy

IF 2.8 4区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Therapeutics Pub Date : 2026-02-24 DOI:10.1155/cdr/8493694

Hua-Jie Zheng, Rui-Han Xiao, Mao-Ting Ye, Jun Li, Mei Guo, San-Jiu Yu, Yong-Bo Cheng, Wei Cheng

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引用次数: 0

Abstract

Aim

The aim of this study is to share our experience of the combined double-orifice and single-patch technique for the correction of partial atrioventricular septal defect (pAVSD) and its associated tricuspid valve dysplasia (TVD).

Methods

Between January 2014 and May 2024, 99 patients (age ≥ 18 years) who underwent repair of pAVSD and its associated TVD using the aforementioned strategy were retrospectively analyzed.

Results

The mean aortic cross-clamp time was 48.5 ± 12.6 min, and the mean cardiopulmonary bypass time was 75.8 ± 13.0 min. Follow-up was 100% at a mean of 5.2 years (3–8 years). No operative or late deaths occurred. No evidence of mitral stenosis was detected, and only one patient developed a severe MR 2 years after the surgery and underwent reoperation. There was no moderate or severe tricuspid regurgitation during follow-up. There was neither secondary tricuspid valve repair nor permanent pacemaker implantation among all patients.

Conclusions

The combined double-orifice and single-patch technique is a safe, effective, and durable strategy for repair of pAVSD and its associated TVD, demonstrating an excellent technical reproducibility.

Abstract Image

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双孔单贴片联合技术治疗成人部分房室间隔缺损：一种新策略。

目的：本研究的目的是分享双孔单补片联合技术治疗部分房室间隔缺损（pAVSD）及其相关的三尖瓣发育不良（TVD）的经验。方法：回顾性分析2014年1月至2024年5月期间99例（年龄≥18岁）采用上述策略修复pAVSD及其相关TVD的患者。结果：主动脉交叉夹持时间平均为48.5±12.6 min，体外循环时间平均为75.8±13.0 min。随访率100%，平均5.2年（3-8年）。未发生手术死亡或晚期死亡。没有发现二尖瓣狭窄的证据，只有1例患者在术后2年发生严重的MR并再次手术。随访期间无中度或重度三尖瓣反流。所有患者均无继发性三尖瓣修复和永久性起搏器植入。结论：双孔单补片联合技术是一种安全、有效、持久的修复pAVSD及其相关TVD的策略，具有良好的技术可重复性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiovascular Therapeutics 医学-心血管系统

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： Cardiovascular Therapeutics (formerly Cardiovascular Drug Reviews) is a peer-reviewed, Open Access journal that publishes original research and review articles focusing on cardiovascular and clinical pharmacology, as well as clinical trials of new cardiovascular therapies. Articles on translational research, pharmacogenomics and personalized medicine, device, gene and cell therapies, and pharmacoepidemiology are also encouraged. Subject areas include (but are by no means limited to): Acute coronary syndrome Arrhythmias Atherosclerosis Basic cardiac electrophysiology Cardiac catheterization Cardiac remodeling Coagulation and thrombosis Diabetic cardiovascular disease Heart failure (systolic HF, HFrEF, diastolic HF, HFpEF) Hyperlipidemia Hypertension Ischemic heart disease Vascular biology Ventricular assist devices Molecular cardio-biology Myocardial regeneration Lipoprotein metabolism Radial artery access Percutaneous coronary intervention Transcatheter aortic and mitral valve replacement.