Prevalence and Outcomes of Frailty in Older Men-the Manitoba Follow-Up Study.

IF 1.2 Q4 GERIATRICS & GERONTOLOGY

Canadian Geriatrics Journal Pub Date : 2026-03-04 eCollection Date: 2026-03-01 DOI:10.5770/cgj.29.907

Philip D St John, Robert B Tate

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引用次数: 0

Abstract

Background: The Frailty Index (FI) is a measure of frailty with recent guidance on its calculation. Objectives were: 1) To determine the prevalence of frailty and its component domains at different ages in older men; and 2) To determine if the FI, and/or its component scores predict death or long-term care (LTC) admission. Design: A cohort study. Setting: Most of the participants lived in Canada. Subjects: 3,983 men who qualified for air crew training during the Second World War. We included 1,711 men (mean age 76) free of dementia, living in the community, who had data to construct a FI in 1996.

Methods: Medical conditions have been measured from 1948. Functional status, health status, and social well-being have been measured by survey since 1996. We constructed a FI from these data and calculated the prevalence of frailty from the age of 75+. We considered three domains of frailty: medical, functional, and psychosocial. We calculated the mortality risk and the risk of LTC care admission using proportional hazards models.

Results: Frailty, dementia, and LTC use are all strongly related to age. The FI is associated with mortality and LTC admission at all ages. This effect was a spectrum of risk. The effect of functional domains was seen at all ages, while the effect of medical conditions on these outcomes declined with advancing age. Psychosocial domains were less strongly correlated with these outcomes.

Conclusions: The FI is associated with adverse outcomes, and should be considered in clinical and policy decisions.

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老年男性衰弱的患病率和结果——马尼托巴随访研究。

背景：脆弱指数（FI）是一种衡量脆弱程度的指标，最近对其计算给出了指导。目的：1)确定老年男性不同年龄段的衰弱患病率及其组成域；2)确定FI和/或其组成评分是否预测死亡或长期护理（LTC）入院。设计：队列研究。环境：大多数参与者居住在加拿大。研究对象：二战期间3983名有资格接受空勤训练的男性。我们纳入了1711名居住在社区的无痴呆男性（平均年龄76岁），他们在1996年有数据构建FI。方法：从1948年开始测量医疗状况。自1996年以来，通过调查测量了功能状况、健康状况和社会福利。我们根据这些数据构建了一个FI，并计算了从75岁以上开始的虚弱患病率。我们考虑了脆弱的三个领域：医学、功能和社会心理。我们使用比例风险模型计算死亡率风险和LTC住院风险。结果：虚弱、痴呆和LTC使用都与年龄密切相关。FI与所有年龄段的死亡率和LTC入院率相关。这种影响是一个风险范围。功能域的影响在所有年龄段都可以看到，而医疗条件对这些结果的影响随着年龄的增长而下降。心理社会领域与这些结果的相关性较弱。结论：FI与不良结果相关，应在临床和政策决策中予以考虑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Canadian Geriatrics Journal Nursing-Gerontology

CiteScore

5.20

自引率

0.00%

发文量

期刊介绍： The Canadian Geriatrics Journal (CGJ) is a peer-reviewed publication that is a home for innovative aging research of a high quality aimed at improving the health and the care provided to older persons residing in Canada and outside our borders. While we gratefully accept submissions from researchers outside our country, we are committed to encouraging aging research by Canadians. The CGJ is targeted to family physicians with training or an interest in the care of older persons, specialists in geriatric medicine, geriatric psychiatrists, and members of other health disciplines with a focus on gerontology.