Eun Mi Yang, Jong Im Won, Sang Heon Suh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
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引用次数: 0
Abstract
Background: Obesity is a known risk factor for diabetes mellitus (DM) and chronic kidney disease (CKD), yet the relationship between various obesity-related indices and CKD remains unclear. This study evaluated the associations between eight obesity indices with CKD and identified the most useful index among patients with DM.
Methods: This study used data from the Korean National Health and Nutrition Examination Survey conducted from 2007 to 2018. A total of 5,067 participants aged ≥ 20 years with DM were included. The study evaluated four traditional anthropometric obesity indices (body mass index [BMI], waist-to-height ratio [WHtR], body roundness index [BRI], conicity index [CI]) and four biochemical-anthropometric indices, including two Asian-specific indices (lipid accumulation product [LAP], visceral adiposity index [VAI], Chinese visceral adiposity index [CVAI], and new visceral adiposity index [NVAI]).
Results: WHtR, BRI, CI, CVAI, and NVAI were higher in males with CKD, while only CI, CVAI, and NVAI were elevated in females. All eight indices were independently associated with CKD risk in males, whereas only the anthropometric-biochemical indices LAP, VAI, and CVAI were significantly associated with CKD in females. NVAI in males and CVAI in females exhibited the highest area under the curve values of 0.615 and 0.658, respectively.
Conclusions: Various obesity indices were associated with CKD in patients with DM, although the associations differed by sex. Asian-specific indices may be the most useful for reflecting CKD in patients with DM.
期刊介绍：
Clinical and Experimental Nephrology is a peer-reviewed monthly journal, officially published by the Japanese Society of Nephrology (JSN) to provide an international forum for the discussion of research and issues relating to the study of nephrology. Out of respect for the founders of the JSN, the title of this journal uses the term “nephrology,” a word created and brought into use with the establishment of the JSN (Japanese Journal of Nephrology, Vol. 2, No. 1, 1960). The journal publishes articles on all aspects of nephrology, including basic, experimental, and clinical research, so as to share the latest research findings and ideas not only with members of the JSN, but with all researchers who wish to contribute to a better understanding of recent advances in nephrology. The journal is unique in that it introduces to an international readership original reports from Japan and also the clinical standards discussed and agreed by JSN.
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