Cody R Kilar, Harjot Kaur Bajwa, Phillip M Pifer, Sushil Beriwal
{"title":"Selection of hybrid applicators for adaptive cervical cancer brachytherapy: A practical guide.","authors":"Cody R Kilar, Harjot Kaur Bajwa, Phillip M Pifer, Sushil Beriwal","doi":"10.5114/jcb.2025.158016","DOIUrl":null,"url":null,"abstract":"<p><p>Image-based adaptive brachytherapy (IGABT) is now the standard of care for patients with locally advanced cervical cancer. EMBRACE-2 MRI-based brachytherapy study demonstrated improved local control rates and reduced morbidity using hybrid applicators. Utilization of these hybrid applicators in gynecological brachytherapy offers advantages over conventional interstitial techniques; however, practical guidance for applicator selection based on disease extent and image findings remains limited. This manuscript aimed to provide a practical framework for applicator selection based on five case scenarios to demonstrate optimal applicator selection tailored to disease extent and anatomical considerations.</p>","PeriodicalId":51305,"journal":{"name":"Journal of Contemporary Brachytherapy","volume":"17 6","pages":"390-399"},"PeriodicalIF":1.1000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12928137/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Contemporary Brachytherapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5114/jcb.2025.158016","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/12/18 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Image-based adaptive brachytherapy (IGABT) is now the standard of care for patients with locally advanced cervical cancer. EMBRACE-2 MRI-based brachytherapy study demonstrated improved local control rates and reduced morbidity using hybrid applicators. Utilization of these hybrid applicators in gynecological brachytherapy offers advantages over conventional interstitial techniques; however, practical guidance for applicator selection based on disease extent and image findings remains limited. This manuscript aimed to provide a practical framework for applicator selection based on five case scenarios to demonstrate optimal applicator selection tailored to disease extent and anatomical considerations.
期刊介绍:
The “Journal of Contemporary Brachytherapy” is an international and multidisciplinary journal that will publish papers of original research as well as reviews of articles. Main subjects of the journal include: clinical brachytherapy, combined modality treatment, advances in radiobiology, hyperthermia and tumour biology, as well as physical aspects relevant to brachytherapy, particularly in the field of imaging, dosimetry and radiation therapy planning. Original contributions will include experimental studies of combined modality treatment, tumor sensitization and normal tissue protection, molecular radiation biology, and clinical investigations of cancer treatment in brachytherapy. Another field of interest will be the educational part of the journal.