Selection of hybrid applicators for adaptive cervical cancer brachytherapy: A practical guide.

IF 1.1 4区 医学 Q4 ONCOLOGY
Journal of Contemporary Brachytherapy Pub Date : 2025-12-01 Epub Date: 2025-12-18 DOI:10.5114/jcb.2025.158016
Cody R Kilar, Harjot Kaur Bajwa, Phillip M Pifer, Sushil Beriwal
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引用次数: 0

Abstract

Image-based adaptive brachytherapy (IGABT) is now the standard of care for patients with locally advanced cervical cancer. EMBRACE-2 MRI-based brachytherapy study demonstrated improved local control rates and reduced morbidity using hybrid applicators. Utilization of these hybrid applicators in gynecological brachytherapy offers advantages over conventional interstitial techniques; however, practical guidance for applicator selection based on disease extent and image findings remains limited. This manuscript aimed to provide a practical framework for applicator selection based on five case scenarios to demonstrate optimal applicator selection tailored to disease extent and anatomical considerations.

适应性宫颈癌近距离放疗混合应用器的选择:实用指南。
基于图像的适应性近距离放射治疗(IGABT)现在是局部晚期宫颈癌患者的标准治疗方法。基于恩布拉-2 mri的近距离治疗研究表明,使用混合涂抹器可提高局部控制率并降低发病率。在妇科近距离治疗中使用这些混合涂布器比传统的间质技术具有优势;然而,基于疾病程度和图像发现的施药器选择的实用指导仍然有限。该手稿旨在提供一个实用的框架,基于五个案例场景的涂抹器选择,以展示适合疾病程度和解剖考虑的最佳涂抹器选择。
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来源期刊
Journal of Contemporary Brachytherapy
Journal of Contemporary Brachytherapy ONCOLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
CiteScore
2.40
自引率
14.30%
发文量
54
审稿时长
16 weeks
期刊介绍: The “Journal of Contemporary Brachytherapy” is an international and multidisciplinary journal that will publish papers of original research as well as reviews of articles. Main subjects of the journal include: clinical brachytherapy, combined modality treatment, advances in radiobiology, hyperthermia and tumour biology, as well as physical aspects relevant to brachytherapy, particularly in the field of imaging, dosimetry and radiation therapy planning. Original contributions will include experimental studies of combined modality treatment, tumor sensitization and normal tissue protection, molecular radiation biology, and clinical investigations of cancer treatment in brachytherapy. Another field of interest will be the educational part of the journal.
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