Screening Breast MRI and Genetic Testing Utilization in High-risk Population: Analysis of National Health Interview Survey.

IF 1.7 Q3 ONCOLOGY

Journal of Breast Imaging Pub Date : 2026-07-28 DOI:10.1093/jbi/wbaf084

Ishana Maini, Kevin Gilotra, Maedeh Sharifian, Nina Capiro, Gelareh Sadigh

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引用次数: 0

Abstract

Objective: For individuals at increased risk of breast cancer, additional tests, such as screening breast MRI and genetic testing, are recommended. We assessed the utilization of screening breast MRI and genetic testing among high-risk individuals and identified associated patient factors.

Methods: This retrospective, cross-sectional study used 2023 National Health Interview Survey data. Women aged 25 or older with at least 1 first-degree relative diagnosed with breast cancer before age 50 were included. A survey weight was applied to generate weighted samples representing national estimates. Multivariable logistic regression analysis was used to identify factors associated with screening breast MRI, genetic test discussions, and genetic test completion.

Results: The weighted sample included 6 851 757 women (unweighted n = 920) (mean age, 60.2; 3.1% [199 883/6 486 458] Asian, 14.4% [932 502/6 486 458] Black, 78.1% [5 063 194/6 486 458] White, and 4.4% [290 879/6 486 458] other races). Overall, 12.5% (855 463/6 851 757) were of Hispanic ethnicity. Screening MRI use was reported by 7.9% (506 672/6 417 453) , while 28.8% (1 963 524/6 822 303) discussed and 17.7% (1 209 406/6 830 229) completed genetic testing. Having 2 or more first-degree relatives with breast cancer increased the likelihood of screening MRI (odds ratio [OR], 2.94; 95% CI, 1.56-5.54) and genetic testing completion (OR, 2.74; 95% CI, 1.68-4.48). The odds of discussing genetic testing were lower for Black individuals (OR, 0.43; 95% CI, 0.20-0.91) and those with Medicaid or no insurance (OR, 0.45; 95% CI, 0.23-0.87). Concern about medical bills was associated with lower odds of genetic testing completion (OR, 0.54; 95% CI, 0.33-0.90).

Conclusions: Screening breast MRI and genetic testing are underutilized among high-risk women. Expanding insurance coverage and provider education may help increase uptake of recommended screening practices.

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高危人群乳腺MRI筛查与基因检测应用：全国健康访谈调查分析。

目的：对于乳腺癌风险增加的个体，建议进行额外的检查，如乳腺MRI筛查和基因检测。我们评估了乳腺MRI筛查和基因检测在高危人群中的应用，并确定了相关的患者因素。方法：采用2023年全国健康访谈调查数据进行回顾性横断面研究。年龄在25岁或以上且至少有一位一级亲属在50岁之前被诊断为乳腺癌的女性被纳入研究。采用调查加权来产生代表国家估计数的加权样本。采用多变量logistic回归分析确定与乳腺MRI筛查、基因检测讨论和基因检测完成相关的因素。结果：加权样本包括6 851 757名女性（未加权n = 920）（平均年龄60.2岁，亚裔3.1%[199 883/6 486 458]，黑人14.4%[932 502/6 486 458]，白人78.1%[5 063 194/6 486 458]，其他种族4.4%[290 879/6 486 458]）。总体而言，12.5%（855 463/6 851 757）为西班牙裔。7.9%（506 672/6 417 453）使用MRI筛查，28.8%（1 963 524/6 822 303）进行了讨论，17.7%（1 209 406/6 830 229）完成了基因检测。有2个或更多的一级亲属患有乳腺癌增加了MRI筛查的可能性（优势比[or]， 2.94; 95% CI, 1.56-5.54）和基因检测完成度（or, 2.74; 95% CI, 1.68-4.48）。讨论基因检测的几率在黑人个体（OR, 0.43; 95% CI, 0.20-0.91）和有医疗补助或没有保险的个体（OR, 0.45; 95% CI, 0.23-0.87）中较低。担心医疗费用与较低的基因检测完成几率相关（OR, 0.54; 95% CI, 0.33-0.90）。结论：乳腺MRI筛查和基因检测在高危女性中未得到充分利用。扩大保险覆盖范围和提供者教育可能有助于增加推荐的筛查做法的采用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Breast Imaging Multiple-

CiteScore

3.40

自引率

20.00%

发文量