Diabetes and Pressure Injury in Critical Care Patients ≥65 Years: The Role of Hemoglobin in Patient Outcomes.

IF 0.9 Q4 CRITICAL CARE MEDICINE

Critical Care Nursing Quarterly Pub Date : 2026-04-01 Epub Date: 2026-02-24 DOI:10.1097/CNQ.0000000000000603

Jenny Alderden, Jonas Prince, Susan M Kennerly, Tracey L Yap

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引用次数: 0

Abstract

Background: Pressure injuries represent a significant healthcare challenge in ICUs, particularly among older adults with diabetes. This study examined the relationship between hemoglobin levels and hospital-acquired pressure injury (HAPrI) development.

Methods: This retrospective cohort study analyzed MIMIC-IV database data from 10,468 ICU patients aged ≥65 years with stays of 2-14 days. Primary outcome was HAPrI development during ICU stay. Clinical and laboratory factors were compared between diabetic and non-diabetic patients.

Results: Among 10,468 patients (mean age 77.56±8.05 years), 366 (3.5%) developed HAPrIs. Diabetes patients (n=1,513, 14.5%) had significantly higher HAPrI rates than non-diabetic patients (6.3% vs 3.0%; P<0.001). Diabetic patients who developed HAPrIs had markedly lower minimum hemoglobin levels than those without HAPrIs (7.94±2.07 vs 10.00±1.73 g/dL; P<0.001). Among diabetic patients with HAPrIs, those developing multiple injuries had lower hemoglobin levels than those with single injuries (7.22±2.06 vs 8.30±2.00 g/dL; P=0.02).

Conclusions: Low hemoglobin levels are strongly associated with HAPrI development in older ICU patients with diabetes, with anemia severity correlating with multiple injury occurrence. Hemoglobin optimization may represent an important targeted prevention strategy for high-risk ICU patients.

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≥65岁重症监护患者的糖尿病和压力性损伤：血红蛋白在患者预后中的作用

背景：压力损伤是icu中一个重要的医疗保健挑战，特别是在老年糖尿病患者中。本研究探讨了血红蛋白水平与医院获得性压力损伤（HAPrI）发展之间的关系。方法：本回顾性队列研究分析了MIMIC-IV数据库中10468例年龄≥65岁、住院时间2-14天的ICU患者的数据。主要预后指标为ICU住院期间HAPrI的发展情况。比较糖尿病与非糖尿病患者的临床及实验室因素。结果：10468例患者（平均年龄77.56±8.05岁）中，366例（3.5%）发生hapri。糖尿病患者（n= 1513, 14.5%）的HAPrI发生率显著高于非糖尿病患者（6.3% vs 3.0%）。结论：低血红蛋白水平与老年ICU糖尿病患者HAPrI发生密切相关，贫血严重程度与多发损伤发生相关。血红蛋白优化可能是高危ICU患者的一种重要的针对性预防策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Critical Care Nursing Quarterly CRITICAL CARE MEDICINE-

CiteScore

2.60

自引率

0.00%

发文量

期刊介绍： Critical Care Nursing Quarterly (CCNQ) is a peer-reviewed journal that provides current practice-oriented information for the continuing education and improved clinical practice of critical care professionals, including nurses, physicians, and allied health care professionals.