Multimycotoxin analysis in Brazilian beer and health risk assessment.

IF 2.6 3区农林科学 Q2 CHEMISTRY, APPLIED

Food additives & contaminants. Part B, Surveillance Pub Date : 2026-06-01 Epub Date: 2026-02-24 DOI:10.1080/19393210.2026.2619157

Leisli Maira Delarmelino Ferraresi, Naiara Hennig Neuenfeldt, Adriana Pavesi Arisseto-Bragotto, Rozilaine Aparecida Pelegrine Gomes de Faria, Liliana De Oliveira Rocha

{"title":"Multimycotoxin analysis in Brazilian beer and health risk assessment.","authors":"Leisli Maira Delarmelino Ferraresi, Naiara Hennig Neuenfeldt, Adriana Pavesi Arisseto-Bragotto, Rozilaine Aparecida Pelegrine Gomes de Faria, Liliana De Oliveira Rocha","doi":"10.1080/19393210.2026.2619157","DOIUrl":null,"url":null,"abstract":"This study validated an analytical method for the simultaneous quantification of 13 mycotoxins in beer using online solid-phase extraction coupled with UPLC-MS/MS and assessed their occurrence in 87 Brazilian samples, including alcoholic and non-alcoholic beers. The method showed high sensitivity, selectivity and linearity (R2 > 0.99), with acceptable recovery and precision, except for ochratoxin A and nivalenol at higher levels. Mycotoxins were detected in 94.3% of the samples. Fumonisin B1 was the most frequent mycotoxin, while 15-acetyldeoxynivalenol had the highest mean level (190 ng/mL). Ochratoxin A was not detected. Estimated daily intake data were compared with toxicological reference values. Although exposure levels were generally below health-based guidance values, margin of exposure analysis indicated potential concern regarding aflatoxin intake. These results underscore the need for continuous monitoring to ensure consumer safety and minimise health risks associated with chronic exposure to mycotoxins through beer consumption.","PeriodicalId":12286,"journal":{"name":"Food additives & contaminants. Part B, Surveillance","volume":" ","pages":"105-115"},"PeriodicalIF":2.6000,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food additives & contaminants. Part B, Surveillance","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1080/19393210.2026.2619157","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/2/24 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}

引用次数: 0

Abstract

This study validated an analytical method for the simultaneous quantification of 13 mycotoxins in beer using online solid-phase extraction coupled with UPLC-MS/MS and assessed their occurrence in 87 Brazilian samples, including alcoholic and non-alcoholic beers. The method showed high sensitivity, selectivity and linearity (R² > 0.99), with acceptable recovery and precision, except for ochratoxin A and nivalenol at higher levels. Mycotoxins were detected in 94.3% of the samples. Fumonisin B1 was the most frequent mycotoxin, while 15-acetyldeoxynivalenol had the highest mean level (190 ng/mL). Ochratoxin A was not detected. Estimated daily intake data were compared with toxicological reference values. Although exposure levels were generally below health-based guidance values, margin of exposure analysis indicated potential concern regarding aflatoxin intake. These results underscore the need for continuous monitoring to ensure consumer safety and minimise health risks associated with chronic exposure to mycotoxins through beer consumption.

查看原文本刊更多论文

巴西啤酒中多霉菌毒素分析及健康风险评估。

本研究验证了在线固相萃取联用UPLC-MS/MS同时定量啤酒中13种真菌毒素的分析方法，并评估了它们在87份巴西样品中的含量，包括含酒精和不含酒精的啤酒。除赭曲霉毒素A和雪缬酚含量较高外，该方法具有较高的灵敏度、选择性和线性（R2 > 0.99），回收率和精密度均可接受。94.3%的样品检出真菌毒素。伏马菌素B1是最常见的真菌毒素，15-乙酰脱氧雪腐镰刀菌醇的平均含量最高（190 ng/mL）。未检出赭曲霉毒素A。估计的每日摄入量数据与毒理学参考值进行了比较。虽然接触水平一般低于以健康为基础的指导值，但接触限度分析表明，黄曲霉毒素的摄入可能令人担忧。这些结果强调了持续监测的必要性，以确保消费者的安全，并尽量减少与通过啤酒长期接触真菌毒素相关的健康风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Food additives & contaminants. Part B, Surveillance 农林科学-毒理学

CiteScore

5.30

自引率

10.30%

发文量

审稿时长

2.7 months

期刊介绍： Food Additives & Contaminants: Part B publishes surveillance data indicating the presence and levels of occurrence of designated food additives, residues and contaminants in foods, food supplements and animal feed. Data using validated methods must meet stipulated quality standards to be acceptable and must be presented in a prescribed format for subsequent data-handling. Food Additives & Contaminants: Part B restricts its scope to include certain classes of food additives, residues and contaminants. This is based on a goal of covering those areas where there is a need to record surveillance data for the purposes of exposure and risk assessment. The scope is initially restricted to: Additives - food colours, artificial sweeteners, and preservatives; Residues – veterinary drug and pesticide residues; Contaminants – metals, mycotoxins, phycotoxins, plant toxins, nitrate/nitrite, PCDDs/PCFDs, PCBs, PAHs, acrylamide, 3-MPCD and contaminants derived from food packaging. Readership: The readership includes scientists involved in all aspects of food safety and quality and particularly those involved in monitoring human exposure to chemicals from the diet. Papers reporting surveillance data in areas other than the above should be submitted to Part A . The scope of Part B will be expanded from time-to-time to ensure inclusion of new areas of concern.