Brain necrosis induced by intranasal cocaine in a patient with a history of craniofacial resection: A case report.

Elena Marin-Diez, Jaime Viera-Artiles, David Mato-Mañas, Enrique Marco de Lucas
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Abstract

A 57-year-old male woodworker was diagnosed with T3N0M0 intestinal-type nasal adenocarcinoma in 2021. He underwent endoscopic craniofacial resection and radiotherapy, with no recurrence for three years. In 2024, he presented with occipital headache and vomiting, revealing a frontal necrotic-hemorrhagic lesion with acute hydrocephalus, initially suspected to be a brain abscess. However, a history of cocaine use suggested brain necrosis facilitated by prior surgery. This unique case demonstrates brain necrosis directly attributable to intranasal cocaine use. Surgeons should consider substance use as a contributing factor in postoperative complications after skull base surgery.

有颅面切除术史的患者鼻内可卡因致脑坏死1例。
一名57岁的男性木工于2021年被诊断为T3N0M0肠型鼻腺癌。经内镜颅面切除术及放疗,三年无复发。2024年,患者出现枕部头痛和呕吐,显示额部坏死性出血性病变伴急性脑积水,最初怀疑为脑脓肿。然而,可卡因使用史表明先前的手术促进了脑坏死。这个独特的病例表明脑坏死直接归因于鼻内可卡因的使用。外科医生应考虑药物使用是颅底手术术后并发症的一个因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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