Clinical and radiological outcomes of ACDF using titanium-screw PEEK cages: A retrospective series

Neurocirugia (English Edition) Pub Date : 2026-09-01 Epub Date: 2026-02-20 DOI:10.1016/j.neucie.2026.500778
Francisco Verdú López, Vicente Vanaclocha, Alejandra Hernández-Valido, David Aliaga, José-María Gallego-Sánchez, Ana-María Morales-Codina
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Abstract

Objective

To evaluate the clinical and radiological outcomes of anterior cervical discectomy and fusion (ACDF) using titanium-screw PEEK cages, focusing on fusion rates, cervical alignment, pain relief, and complications.

Methods

Retrospective observational study of 40 consecutive patients treated between May 2017 and December 2018. Outcomes included Neck Disability Index (NDI), Numerical Rating Scale (NRS) for cervical and radicular pain, and radiological parameters (fusion status, Cobb angles, disk height). Complications were systematically documented, and longitudinal changes were analyzed using the Friedman test for repeated measures.

Results

At 2-year follow-up, all patients achieved radiological fusion (Bridwell grades I–II). Median NDI improved from 56% to 20% (p < 0.001). Cervical and radicular pain scores decreased significantly (median NRS from 8 to 2 and 7 to 1; p < 0.001). Cervical alignment and disk height improved and remained stable. Dysphagia and dysphonia occurred in 5% and 2.5% of cases, respectively, resolving spontaneously.

Conclusions

ACDF using titanium-screw PEEK cages is safe and effective, providing high fusion rates, significant clinical improvement, and low complication rates. These zero-profile hybrid devices offer a reliable alternative to traditional cage-plate constructs.
使用钛螺钉PEEK笼治疗ACDF的临床和放射学结果:回顾性研究。
目的:评价使用钛螺钉PEEK保持器进行前路颈椎椎间盘切除术和融合(ACDF)的临床和放射学结果,重点关注融合率、颈椎对准、疼痛缓解和并发症。方法:对2017年5月至2018年12月连续治疗的40例患者进行回顾性观察研究。结果包括颈部残疾指数(NDI)、颈椎和神经根疼痛的数值评定量表(NRS)和放射学参数(融合状态、Cobb角、椎间盘高度)。系统地记录并发症,并使用重复测量的Friedman检验分析纵向变化。结果:在2年的随访中,所有患者都实现了放射融合(Bridwell分级I-II)。中位NDI从56%提高到20% (p < 0.001)。颈椎和神经根疼痛评分显著下降(中位NRS从8降至2,从7降至1;p < 0.001)。颈椎直线和椎间盘高度改善并保持稳定。吞咽困难和发音困难分别发生在5%和2.5%的病例中,自发消退。结论:ACDF使用钛螺钉PEEK保持器安全有效,融合率高,临床改善显著,并发症发生率低。这些零轮廓混合装置为传统的笼型板结构提供了可靠的替代方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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