Genetic analysis of human breast cancer: a synthesis of contributions to GAW IV.

Abstract

A variety of reports on the genetic epidemiology of breast cancer appeared prior to GAW IV, including segregation and linkage results which are not always in agreement. Additionally, various viewpoints regarding sampling, ascertainment and modelling have been raised during the history of the study of the genetic epidemiology of breast cancer. Since these analyses have been performed on different data sets by different investigators there had previously been no method of coming to general conclusions concerning the epidemiology of this disease.