Histiocytosis-X of the hypothalamus: Case report and literature review

Abstract

Involvement of the central nervous system (CNS) in patients with histiocytosis-X manifesting secondary hormonal change is well known clinically. Proof of involvement of the most common CNS focus, the hypothalamus., is also seen in autopsy cases on occasion. However, premortem radiographic evidence of hypothalamic infiltration is unusual. Presented is a case report and a brief literature review of such cases.