A crisis of overconfidence: Why confidence, not accuracy, is the real risk in clinical AI.

IF 7.9 3区 生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Jacob S Berkowitz, Jake R Patock, Asma Nawaz, Graciela Gonzalez-Hernandez, Nicholas P Tatonetti
{"title":"A crisis of overconfidence: Why confidence, not accuracy, is the real risk in clinical AI.","authors":"Jacob S Berkowitz, Jake R Patock, Asma Nawaz, Graciela Gonzalez-Hernandez, Nicholas P Tatonetti","doi":"10.1186/s13040-026-00518-4","DOIUrl":null,"url":null,"abstract":"<p><p>Language models today are trained to convey confidence in their outputs, regardless of whether those outputs are correct. The alignment methods we use to make them helpful also push them toward unwarranted certainty, rewarding decisive answers over appropriate hedging. As these foundation models enter high-stakes domains such as science and medicine, this disconnect between how sure they sound and how accurate they are can become dangerous. Here, we examine why post-training degrades a model’s sense of uncertainty, and we review techniques that can bring expressed confidence back in line with actual reliability. Through this, we argue that trustworthy AI means treating calibration as a core design goal.</p>","PeriodicalId":48947,"journal":{"name":"Biodata Mining","volume":"19 1","pages":"10"},"PeriodicalIF":7.9000,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12874690/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biodata Mining","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1186/s13040-026-00518-4","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATHEMATICAL & COMPUTATIONAL BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Language models today are trained to convey confidence in their outputs, regardless of whether those outputs are correct. The alignment methods we use to make them helpful also push them toward unwarranted certainty, rewarding decisive answers over appropriate hedging. As these foundation models enter high-stakes domains such as science and medicine, this disconnect between how sure they sound and how accurate they are can become dangerous. Here, we examine why post-training degrades a model’s sense of uncertainty, and we review techniques that can bring expressed confidence back in line with actual reliability. Through this, we argue that trustworthy AI means treating calibration as a core design goal.

过度自信的危机:为什么临床人工智能的真正风险是自信,而不是准确性。
今天的语言模型被训练成在其输出中传达信心,而不管这些输出是否正确。我们用来使它们有用的校准方法也将它们推向毫无根据的确定性,奖励果断的答案而不是适当的对冲。当这些基础模型进入诸如科学和医学等高风险领域时,它们听起来有多可靠与它们有多准确之间的脱节可能会变得危险。在这里,我们研究了为什么训练后会降低模型的不确定感,并且我们回顾了可以将表达的信心恢复到与实际可靠性一致的技术。通过这一点,我们认为值得信赖的人工智能意味着将校准作为核心设计目标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Biodata Mining
Biodata Mining MATHEMATICAL & COMPUTATIONAL BIOLOGY-
CiteScore
7.90
自引率
0.00%
发文量
28
审稿时长
23 weeks
期刊介绍: BioData Mining is an open access, open peer-reviewed journal encompassing research on all aspects of data mining applied to high-dimensional biological and biomedical data, focusing on computational aspects of knowledge discovery from large-scale genetic, transcriptomic, genomic, proteomic, and metabolomic data. Topical areas include, but are not limited to: -Development, evaluation, and application of novel data mining and machine learning algorithms. -Adaptation, evaluation, and application of traditional data mining and machine learning algorithms. -Open-source software for the application of data mining and machine learning algorithms. -Design, development and integration of databases, software and web services for the storage, management, retrieval, and analysis of data from large scale studies. -Pre-processing, post-processing, modeling, and interpretation of data mining and machine learning results for biological interpretation and knowledge discovery.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书