Recurrent Eosinophilic Angiocentric Fibrosis Presenting as Compressive Optic Neuropathy in a 39-Year-Old Male: A Case Report.

IF 0.6 Q4 CLINICAL NEUROLOGY
Neuro-Ophthalmology Pub Date : 2025-03-31 eCollection Date: 2026-01-01 DOI:10.1080/01658107.2025.2485454
Priyanka Arora, Yesha Gupta, Ishaan Goyal, Abhinav Mohindra, Monika Singla
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引用次数: 0

Abstract

Eosinophilic angiocentric fibrosis (EAF) is a rare, slowly progressive fibrosing condition with a predilection for the upper respiratory tract, particularly the nasal cavity. Patients often present with nonspecific nasal symptoms and may experience rare ocular manifestations such as epiphora, diplopia, and proptosis. We report a case of a 39-year-old male who presented with sudden-onset vision loss, ptosis in right eye and diplopia, which was found to be associated with recurrent EAF leading to compressive optic neuropathy. Despite initial management with intravenous steroids, the patient showed no improvement and was subsequently treated with rituximab. This case highlights the importance of considering EAF in the differential diagnosis of orbital masses and emphasizes the role of immunosuppression in managing recurrent cases.

39岁男性复发性嗜酸性血管中心性纤维化表现为压迫性视神经病变1例报告。
嗜酸性血管中心性纤维化(EAF)是一种罕见的、缓慢进展的纤维化疾病,多发生于上呼吸道,尤其是鼻腔。患者通常表现为非特异性鼻部症状,并可能出现罕见的眼部表现,如眼显、复视和眼球突出。我们报告一个39岁男性的病例,他表现为突发性视力丧失,右眼上睑下垂和复视,这被发现与复发性EAF导致压缩性视神经病变有关。尽管最初使用静脉注射类固醇治疗,但患者没有好转,随后使用利妥昔单抗治疗。本病例强调了在眼眶肿块鉴别诊断中考虑EAF的重要性,并强调了免疫抑制在治疗复发病例中的作用。
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来源期刊
Neuro-Ophthalmology
Neuro-Ophthalmology 医学-临床神经学
CiteScore
1.80
自引率
0.00%
发文量
51
审稿时长
>12 weeks
期刊介绍: Neuro-Ophthalmology publishes original papers on diagnostic methods in neuro-ophthalmology such as perimetry, neuro-imaging and electro-physiology; on the visual system such as the retina, ocular motor system and the  pupil; on neuro-ophthalmic aspects of the orbit; and on related fields such as migraine and ocular manifestations of neurological diseases.
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