Hybrid one-stage Snodgrass-Duckett urethroplasty for severe hypospadias. A five-year institutional experience.

Q3 Medicine
Nikolaos Baltogiannis, Fotini Fili, Ileana Vasiliki Baltogianni, Evangelos Papandreou
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Abstract

Proximal and complex hypospadias repairs remain among the most technically demanding procedures in pediatric urology, particularly in patients with inadequate local tissue or previous failed reconstructions. This study reports a five-year institutional experience with a single-stage hybrid technique combining the Snodgrass Tubularized Incised Plate (TIP) repair and the Duckett transverse preputial island flap urethroplasty. Between 2019 and 2024, forty-two patients with severe hypospadias underwent hybrid Snodgrass- Duckett urethroplasty at our institution. Patients were categorized as: Group A (n = 12) with 46,XY Disorders of Sexual Development (DSD); Group B (n = 16) with primary proximal perineoscrotal hypospadias; and Group C (n = 14) with multiple failed prior repairs. The proximal urethra was reconstructed using a Tubularized Native Plate (TNP) and the distal segment with a tubularized preputial island flap (Duckett), joined via an oblique anastomosis. Penile curvature correction and ventral coverage were achieved using lateral flaps. Functional and cosmetic outcomes, as well as complications, were recorded prospectively. A glans-tip meatus was achieved in all patients. Cosmetic appearance was deemed satisfactory in all cases. Uroflowmetry was normal in 95.2% (40/42; 95% CI 86.6- 100). Complications occurred in seven patients (16.7%; 95% CI 5.6-27.7), including urethrocutaneous fistula (n = 4), diverticulum (n = 1), and early breakdown (n = 2), all successfully corrected. Median follow-up was 26 months (IQR 18-36). No urethral strictures or meatal stenosis developed during follow-up. The hybrid Snodgrass-Duckett urethroplasty represents a feasible single-stage alter- native for selected severe hypospadias cases, including reoperative and DSD patients, when local tissue is insufficient. The approach combines the vascular reliability of the preputial flap with the stability of the native urethral plate. While results are encouraging, the retrospective design, absence of a control group, and heterogeneity of the cohort limit generalizability. Prospective multicenter studies with standardized functional and cosmetic scoring are warranted.

混合式一期Snodgrass-Duckett尿道成形术治疗重度尿道下裂。五年的机构经验。
近端和复杂的尿道下裂修复仍然是儿科泌尿外科中技术要求最高的手术,特别是在局部组织不足或先前重建失败的患者中。本研究报告了一种单阶段混合技术结合Snodgrass管状切开钢板(TIP)修复和Duckett横切包皮岛状皮瓣尿道成形术的五年机构经验。在2019年至2024年期间,42名严重尿道下裂患者在我们的机构接受了混合Snodgrass- Duckett尿道成形术。患者分为:A组(n = 12), 46xy性发育障碍(DSD);B组(n = 16)为原发性近阴部会阴尿道下裂;C组(n = 14)先前多次修复失败。尿道近端部采用管状原生板(TNP)重建,远端部采用管状包壳岛状皮瓣(Duckett)重建,并通过斜口吻合连接。阴茎曲率矫正和腹侧覆盖使用外侧皮瓣实现。前瞻性地记录功能和美容结果以及并发症。所有患者均获得了龟头-龟头切口。在所有案例中,美容外观都被认为是令人满意的。95.2%尿流检查正常(40/42;95% CI 86.6- 100)。7例患者出现并发症(16.7%;95% CI 5.6-27.7),包括尿道瘘(n = 4)、憩室(n = 1)和早期衰竭(n = 2),均成功纠正。中位随访26个月(IQR 18-36)。随访期间无尿道狭窄或尿道狭窄发生。混合型Snodgrass-Duckett尿道成成术是一种可行的单阶段替代方法,适用于局部组织不足的严重尿道下裂病例,包括再手术和DSD患者。该方法结合了包皮瓣血管的可靠性和尿道板的稳定性。虽然结果令人鼓舞,但回顾性设计,缺乏对照组,以及队列的异质性限制了推广。采用标准化功能评分和美容评分的前瞻性多中心研究是必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Pediatria Medica e Chirurgica
Pediatria Medica e Chirurgica Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.70
自引率
0.00%
发文量
21
审稿时长
10 weeks
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