Risk of cardiac dysfunction in patients receiving anthracyclines across breast cancer and hematologic malignancies: a single-center retrospective cohort study in Japan.

IF 1.5 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Heart and Vessels Pub Date : 2026-08-01 Epub Date: 2026-02-01 DOI:10.1007/s00380-026-02654-7
Yujiro Homma, Kazuyoshi Kimura, Kenta Sasaki, Yuji Okura, Takeshi Kashimura, Takayuki Inomata, Yasuo Saijo, Qiliang Zhou
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引用次数: 0
接受蒽环类药物治疗的乳腺癌和血液恶性肿瘤患者心功能障碍的风险:日本的一项单中心回顾性队列研究
蒽环类药物广泛用于乳腺癌和血液系统恶性肿瘤,但与癌症治疗相关性心功能障碍(CTRCD)有关。本研究旨在评估心衰协会-国际心脏肿瘤学会(HFA-ICOS)基线风险分层风险工具的临床应用。我们对2016年1月至2024年12月期间首次接受蒽环类化疗的16岁及以上乳腺癌或血液恶性肿瘤患者进行了一项回顾性、单中心队列研究。基线心血管风险根据HFA-ICOS标准分层,CTRCD根据2022年欧洲心脏病学会指南定义。在最终分析队列中纳入的591例患者中,40例(6.8%)在中位3.7年的观察期内(四分位数间距[IQR] 1.6-5.9)发生CTRCD。HFA-ICOS类别的发病率逐步增加(低4.4%,中等8.2%,高/极高22.9%
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来源期刊
Heart and Vessels
Heart and Vessels 医学-外周血管病
CiteScore
3.10
自引率
13.30%
发文量
211
审稿时长
2 months
期刊介绍: Heart and Vessels is an English-language journal that provides a forum of original ideas, excellent methods, and fascinating techniques on cardiovascular disease fields. All papers submitted for publication are evaluated only with regard to scientific quality and relevance to the heart and vessels. Contributions from those engaged in practical medicine, as well as from those involved in basic research, are welcomed.
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