{"title":"Ollama-driven medical insights using LLMs with a federated learning approach","authors":"Gurbaksh Lal , Geetanjali Rathee , Chaker Abdelaziz Kerrache","doi":"10.1016/j.compbiomed.2026.111514","DOIUrl":null,"url":null,"abstract":"<div><div>Traditional medical diagnostics often suffer from delays and inconsistencies due to the manual interpretation of unstructured patient data. To overcome these challenges, we introduce Our Model (given name as ‘AI Doctor’)—a novel diagnostic system built on the Ollama platform that integrates multiple pretrained large language models (Meditron, MedLLaMA2, WizardLM2, and Mistral) through an innovative prompt filtering mechanism. AI Doctor accurately interprets patient-reported symptoms to deliver precise diagnoses and personalized treatment recommendations, while its design supports robust local deployment and includes a theoretical framework for federated learning. This federated approach facilitates decentralized, privacy-preserving model updates across healthcare institutions. Performance evaluations using BLEU scores, structured output analysis, and inference speed measurements demonstrate that AI Doctor consistently outperforms individual models, ensuring high diagnostic accuracy and realtime clinical applicability.</div></div>","PeriodicalId":10578,"journal":{"name":"Computers in biology and medicine","volume":"204 ","pages":"Article 111514"},"PeriodicalIF":6.3000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computers in biology and medicine","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0010482526000752","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/30 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Traditional medical diagnostics often suffer from delays and inconsistencies due to the manual interpretation of unstructured patient data. To overcome these challenges, we introduce Our Model (given name as ‘AI Doctor’)—a novel diagnostic system built on the Ollama platform that integrates multiple pretrained large language models (Meditron, MedLLaMA2, WizardLM2, and Mistral) through an innovative prompt filtering mechanism. AI Doctor accurately interprets patient-reported symptoms to deliver precise diagnoses and personalized treatment recommendations, while its design supports robust local deployment and includes a theoretical framework for federated learning. This federated approach facilitates decentralized, privacy-preserving model updates across healthcare institutions. Performance evaluations using BLEU scores, structured output analysis, and inference speed measurements demonstrate that AI Doctor consistently outperforms individual models, ensuring high diagnostic accuracy and realtime clinical applicability.
期刊介绍:
Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.