{"title":"Alveolar rhabdomyosarcoma with multiple bone marrow metastases: a case report.","authors":"Deqing Song, Yining Xiang, Lu Shen, Lingling Song","doi":"10.1093/bjrcr/uaaf066","DOIUrl":null,"url":null,"abstract":"<p><p>Rhabdomyosarcoma (RMS) is rare but is the most common soft tissue sarcoma in children and teenagers. Alveolar rhabdomyosarcoma (ARMS), a subtype of RMS, primarily affects teenagers aged between 10 and 25 years old and is associated with early lymphatic and hematogenous metastases. This case report describes a 13-year-old girl with ARMS in the right thigh, accompanied by multiple bone and bone marrow metastases. Contrast-enhanced CT/MRI revealed a mass with marked heterogeneous enhancement and an enhancing pseudocapsule, while pathological examination confirmed the diagnosis through immunohistochemical markers (MyoD1 (+), Myogenin (+), Desmin (+)). This case highlights the aggressive nature of ARMS and the importance of characteristic imaging findings.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":"12 1","pages":"uaaf066"},"PeriodicalIF":0.6000,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12812166/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BJR Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/bjrcr/uaaf066","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Rhabdomyosarcoma (RMS) is rare but is the most common soft tissue sarcoma in children and teenagers. Alveolar rhabdomyosarcoma (ARMS), a subtype of RMS, primarily affects teenagers aged between 10 and 25 years old and is associated with early lymphatic and hematogenous metastases. This case report describes a 13-year-old girl with ARMS in the right thigh, accompanied by multiple bone and bone marrow metastases. Contrast-enhanced CT/MRI revealed a mass with marked heterogeneous enhancement and an enhancing pseudocapsule, while pathological examination confirmed the diagnosis through immunohistochemical markers (MyoD1 (+), Myogenin (+), Desmin (+)). This case highlights the aggressive nature of ARMS and the importance of characteristic imaging findings.
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