Ethical dilemmas of living donor kidney transplantation: A systematic review

IF 2.1 4区医学 Q2 UROLOGY & NEPHROLOGY

Nefrologia Pub Date : 2026-01-01 Epub Date: 2025-08-14 DOI:10.1016/j.nefro.2025.501398

María Isabel Rebollo Mateos , José López Castro

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Abstract

Introduction

Living donor kidney transplantation is a crucial treatment for chronic kidney disease, yet it raises significant ethical issues. This systematic review addresses these issues by analysing scientific literature from the past ten years. The objectives include identifying and thoroughly analysing the most common ethical dilemmas, describing them, examining the perspectives of various involved groups, and analysing clinical strategies to address them.

Material and methods

Databases such as PubMed, Scopus, and Mendeley were used, following PRISMA guidelines, and 49 relevant studies were included.

Results

The identified dilemmas encompass equity in access to transplantation, distributive justice, informed consent, transplant tourism, coercion, and ethical issues related to desensitization.

Discussion

The review highlights the need for multidisciplinary approaches and unified protocols to tackle these ethical challenges. It underscores the importance of adhering to fundamental ethical principles, aligning with international bioethical statements.

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活体肾移植的伦理困境：系统综述

活体肾移植是慢性肾脏疾病的重要治疗方法，但它也引起了重大的伦理问题。本系统综述通过分析过去十年的科学文献来解决这些问题。目标包括识别和彻底分析最常见的道德困境，描述它们，检查各种相关群体的观点，并分析临床策略来解决这些问题。材料和方法使用PubMed、Scopus和Mendeley等数据库，遵循PRISMA指南，纳入49项相关研究。结果确定的困境包括移植机会的公平性、分配正义、知情同意、移植旅游、强制以及与脱敏相关的伦理问题。本综述强调需要多学科方法和统一的协议来解决这些伦理挑战。它强调了坚持基本伦理原则，与国际生物伦理声明保持一致的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nefrologia 医学-泌尿学与肾脏学

CiteScore

3.40

自引率

7.70%

发文量

148

审稿时长

47 days

期刊介绍： Nefrología is the official publication of the Spanish Society of Nephrology. The Journal publishes articles on basic or clinical research relating to nephrology, arterial hypertension, dialysis and kidney transplants. It is governed by the peer review system and all original papers are subject to internal assessment and external reviews. The journal accepts submissions of articles in English and in Spanish languages.