Economic Burden of Respiratory Syncytial Virus Infection in Colombia: A Nationwide Cost-of-Illness Study.

IF 2.3 Q2 ECONOMICS

Journal of Health Economics and Outcomes Research Pub Date : 2025-12-19 eCollection Date: 2025-01-01 DOI:10.36469/001c.151678

Giancarlo Buitrago, Paula González-Caicedo, Juan M Reyes-Sanchez, Claudia Burgos, Jair Arciniegas, Jorge La Rotta, Omar Escobar, Andreina Alamo

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Abstract

Background: Respiratory syncytial virus (RSV) is one of the leading causes of acute respiratory infections and severe cases can lead to hospitalization or death. The epidemiology and health resource utilization of RSV infection in Colombia is not well understood. Given the recent availability of new RSV preventatives, this study estimated the economic burden of RSV in Colombia.

Methods: This cost-of-illness study employed a retrospective cohort design and bottom-up costing approach to estimate direct healthcare costs associated with RSV-related acute respiratory infections across pediatric and adult populations. Administrative data from sentinel surveillance centers belonging to the National Epidemiological Surveillance System of the Colombian National Institute of Health, the database for the study of the Capitation Payment Unit database, and the Integrated Social Protection Information System were utilized to estimate RSV incidence, mortality, and healthcare costs. Costs were expressed in US dollars.

Results: A total of 264 744 RSV-related healthcare consultations were identified in 2019. The highest incidence was among infants under 1 year (61.8 per 1000), while general mortality was highest in adults 75 years and older (46.6 per 100,000), followed by infants (42.4 per 100 000). Total direct healthcare costs were estimated at $682.87 m i l l i o n (95$ 281.39 million- $1084.35 m i l l i o n), w i t h t h e l a r g e s t s h a r e c o n t r i b u t e d b y i n d i v i d u a l s a g e d 15 y e a r s a n d o l d e r . A m o n g i n f a n t s u n d e r 1 y e a r, i n t e n s i v e c a r e u n i t (I C U) p a t i e n t s h a d t h e h i g h e s t a v e r a g e c o s t ($ 3619), and hospitalization accounted for 49% of total spending, followed by ICU services (29%) and medications (8%).

Conclusions: RSV poses a significant economic burden on Colombia's healthcare system. These findings support the need for targeted prevention strategies and efficient resource allocation. Future research should incorporate indirect costs and long-term impacts.

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哥伦比亚呼吸道合胞病毒感染的经济负担：一项全国性的疾病成本研究。

背景：呼吸道合胞病毒（RSV）是急性呼吸道感染的主要原因之一，严重者可导致住院或死亡。哥伦比亚RSV感染的流行病学和卫生资源利用情况尚不清楚。鉴于最近出现了新的RSV预防措施，本研究估计了哥伦比亚RSV的经济负担。方法：这项疾病成本研究采用回顾性队列设计和自下而上的成本计算方法来估计儿童和成人rsv相关急性呼吸道感染的直接医疗成本。来自哥伦比亚国立卫生研究院国家流行病学监测系统哨点监测中心的行政数据、用于研究人均支付单位数据库的数据库和综合社会保护信息系统用于估计RSV发病率、死亡率和医疗费用。成本以美元表示。结果：2019年共发现264,744例与rsv相关的医疗咨询。发病率最高的是1岁以下婴儿（每1000人61.8人），而一般死亡率最高的是75岁及以上的成年人（每10万人46.6人），其次是婴儿（每10万人42.4人）。直接医疗成本估计为682.87米我l l i o n(95 2.8139亿- 1084.35 l l i o n), w i t h t h e l r g e s t s h r e c o n t r i b t u e d b y我n d v d u l s g e d 15 y e r s n d o l d e r。m o n g f i n n t s u n d e r 1 y e r,我n t e n s v e c r e u n i t(我c u) p t i e n t s h d t h e h i g h e s t v e r g e c o s t(3619),和住院占总支出的49%,其次是加护病房服务(29%)和药物(8%)。结论：RSV对哥伦比亚的卫生保健系统造成了重大的经济负担。这些发现支持有针对性的预防战略和有效的资源分配的必要性。未来的研究应纳入间接成本和长期影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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