Amanda Karina Santos Vieira, Luiza Paes Barbosa, Juliana Rizzo Gnatta
{"title":"Geranium Essential Oil Use for Human Health: A Systematic Review of Clinical Evidence","authors":"Amanda Karina Santos Vieira, Luiza Paes Barbosa, Juliana Rizzo Gnatta","doi":"10.1002/ffj.70033","DOIUrl":null,"url":null,"abstract":"<p>Essential oils (EOs) form the foundation of aromatherapy, an integrative health practice with ancient roots and scientific validation. Geranium essential oil (GEO) (<i>Pelargonium graveolens</i>) stands out for its versatile pharmacological profile, including anxiolytic, anti-inflammatory and dermatological benefits, alongside its antibacterial and antioxidant properties. This systematic review aimed to evaluate the effectiveness of GEO in the context of human health. A systematic search was conducted in databases (PubMed, EMBASE, Scopus, Web of Science, LILACS, CINAHL, CENTRAL) and grey literature between August and September 2024. The review included randomised controlled trials (RCTs) and quasi-experimental studies assessing the isolated use of GEO in humans, with methodological quality evaluated using JBI tools. Data collection and analysis were performed by two independent reviewers. The main results showed that the review included 12 studies, most of which demonstrated significant efficacy in improving outcomes such as premenstrual syndrome symptoms, dermatological and oral conditions, anxiety and pain, supported by its antioxidant, anti-inflammatory and neurochemical mechanisms. The intervention showed a favourable safety profile and adaptability to different clinical conditions, supporting its potential as a complementary therapy. In conclusion, the review highlights the therapeutic potential of GEO but underscores the need for more diverse and controlled research due to methodological variability (PROSPERO CRD42024601840).</p>","PeriodicalId":170,"journal":{"name":"Flavour and Fragrance Journal","volume":"41 1","pages":"24-36"},"PeriodicalIF":2.5000,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ffj.70033","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Flavour and Fragrance Journal","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ffj.70033","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Essential oils (EOs) form the foundation of aromatherapy, an integrative health practice with ancient roots and scientific validation. Geranium essential oil (GEO) (Pelargonium graveolens) stands out for its versatile pharmacological profile, including anxiolytic, anti-inflammatory and dermatological benefits, alongside its antibacterial and antioxidant properties. This systematic review aimed to evaluate the effectiveness of GEO in the context of human health. A systematic search was conducted in databases (PubMed, EMBASE, Scopus, Web of Science, LILACS, CINAHL, CENTRAL) and grey literature between August and September 2024. The review included randomised controlled trials (RCTs) and quasi-experimental studies assessing the isolated use of GEO in humans, with methodological quality evaluated using JBI tools. Data collection and analysis were performed by two independent reviewers. The main results showed that the review included 12 studies, most of which demonstrated significant efficacy in improving outcomes such as premenstrual syndrome symptoms, dermatological and oral conditions, anxiety and pain, supported by its antioxidant, anti-inflammatory and neurochemical mechanisms. The intervention showed a favourable safety profile and adaptability to different clinical conditions, supporting its potential as a complementary therapy. In conclusion, the review highlights the therapeutic potential of GEO but underscores the need for more diverse and controlled research due to methodological variability (PROSPERO CRD42024601840).
期刊介绍：
Flavour and Fragrance Journal publishes original research articles, reviews and special reports on all aspects of flavour and fragrance. Its high scientific standards and international character is ensured by a strict refereeing system and an editorial team representing the multidisciplinary expertise of our field of research. Because analysis is the matter of many submissions and supports the data used in many other domains, a special attention is placed on the quality of analytical techniques. All natural or synthetic products eliciting or influencing a sensory stimulus related to gustation or olfaction are eligible for publication in the Journal. Eligible as well are the techniques related to their preparation, characterization and safety. This notably involves analytical and sensory analysis, physical chemistry, modeling, microbiology – antimicrobial properties, biology, chemosensory perception and legislation.
The overall aim is to produce a journal of the highest quality which provides a scientific forum for academia as well as for industry on all aspects of flavors, fragrances and related materials, and which is valued by readers and contributors alike.
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