Physiology-guided albumin therapy in decompensated cirrhosis: the expanding role of point-of-care ultrasound

IF 2.6 4区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Clinics and research in hepatology and gastroenterology Pub Date : 2026-01-01 Epub Date: 2025-12-09 DOI:10.1016/j.clinre.2025.102744

Froylan D Martínez-Sánchez , David Aguirre-Villarreal , Eduardo R Argaiz , Luis A Rosales-Rentería , Mario AJ Leal-Villarreal , Ignacio García-Juárez

引用次数: 0

Abstract

Point-of-care ultrasound (POCUS) enables physiology-guided hemodynamic assessment in decompensated cirrhosis, moving beyond protocolized albumin use toward individualized therapy. By integrating IVC/IJV indices, lung ultrasound, and intrarenal venous Doppler, clinicians can tailor albumin and vasopressor strategies to fluid tolerance, potentially improving AKI reversal while limiting overload. We outline a pragmatic bedside framework to operationalize POCUS-guided albumin management in routine hepatology practice.

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生理引导的白蛋白治疗在失代偿期肝硬化：点护理超声的扩大作用。

即时超声（POCUS）能够在失代偿期肝硬化中进行生理引导的血流动力学评估，使白蛋白的使用超越了方案化的使用，向个体化治疗迈进。通过整合IVC/IJV指数、肺超声和肾内静脉多普勒，临床医生可以根据液体耐受性量身定制白蛋白和血管加压策略，在限制负荷的同时潜在地改善AKI逆转。我们概述了一个实用的床边框架，在常规肝病实践中实施pocuss指导的白蛋白管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinics and research in hepatology and gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

4.30

自引率

3.70%

发文量

198

审稿时长

42 days

期刊介绍： Clinics and Research in Hepatology and Gastroenterology publishes high-quality original research papers in the field of hepatology and gastroenterology. The editors put the accent on rapid communication of new research and clinical developments and so called "hot topic" issues. Following a clear Editorial line, besides original articles and case reports, each issue features editorials, commentaries and reviews. The journal encourages research and discussion between all those involved in the specialty on an international level. All articles are peer reviewed by international experts, the articles in press are online and indexed in the international databases (Current Contents, Pubmed, Scopus, Science Direct). Clinics and Research in Hepatology and Gastroenterology is a subscription journal (with optional open access), which allows you to publish your research without any cost to you (unless you proactively chose the open access option). Your article will be available to all researchers around the globe whose institution has a subscription to the journal.