Effects of Sound Frequencies on Pain and Comfort During Intramuscular Injection: A Randomized Controlled Study

Journal of chiropractic medicine Pub Date : 2025-01-01 Epub Date: 2025-10-11 DOI:10.1016/j.jcm.2025.09.010
Saeed Mohammadi MD , Ebrahim Ezzati PhD , Rooghaye Mahooti Bs , Fatemeh Kavyannejad Bs , Rasoul Kavyannejad PhD
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Abstract

Objective

The present study aimed to evaluate the effects of sound frequencies on pain induced by intramuscular injection (IMI).

Methods

This was a double-blind study involving IMI candidates who were randomly divided into 10 equal groups, including intervention, inactive, and control groups (30 patients per group). In the intervention groups, patients received sound stimulation at frequencies ranging from 10 to 200 Hz at 50 dB during IMI. No sound stimulation was provided in the control and inactive groups. Pain and comfort levels were assessed using a visual analog scale, along with monitoring changes in blood pressure and heart rate.

Results

The study results indicated that as sound frequency increased, pain levels decreased compared to the control and inactive groups. The reduction in pain and increase in comfort scores were most significant at frequencies of 150 and 200 Hz. Tachycardia intensity at 150 and 200 Hz was significantly lower than in the inactive and 10 Hz groups. The increase in systolic blood pressure at frequencies of 40 to 200 Hz was significantly lower than in the inactive group, and also at 200 Hz compared to the control and 10 to 50 Hz groups. Additionally, diastolic blood pressure at 200 Hz was significantly lower than in the control, inactive, and 10 to 50 Hz groups.

Conclusion

The study concluded that sound can reduced IMI pain, as well as postinjection changes in blood pressure and heart rate. This nonpharmacological and noninvasive intervention demonstrated greater changes at higher frequencies.
声音频率对肌肉注射疼痛和舒适的影响:一项随机对照研究
目的探讨不同声频对肌内注射(IMI)所致疼痛的影响。方法本研究采用双盲方法,将IMI患者随机分为10组,包括干预组、非活动组和对照组(每组30例)。在干预组中,患者在IMI期间接受频率为10至200 Hz,频率为50 dB的声音刺激。对照组和非活动组不给予声音刺激。使用视觉模拟量表评估疼痛和舒适程度,同时监测血压和心率的变化。结果研究结果表明,与对照组和不活动组相比,随着声音频率的增加,疼痛程度降低。疼痛的减轻和舒适评分的增加在150和200赫兹的频率下最为显著。150和200 Hz时的心动过速强度明显低于不活动组和10 Hz组。在40至200赫兹频率下,收缩压的增加明显低于不活动组,也低于200赫兹频率下的对照组和10至50赫兹组。此外,200 Hz时的舒张压明显低于对照组、不活动组和10至50 Hz组。结论:声音可以减轻IMI疼痛,以及注射后血压和心率的变化。这种非药物和非侵入性干预在更高的频率下显示出更大的变化。
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CiteScore
1.50
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