Wei Nie , Xulong Huang , Jin Pei , Chaoxiang Ren , Tao Zhou , Jinyu Du , Huajuan Jiang , HanYi Zhang , Xin Li , Juan Li , Yuhang Li , Yueying Hu , Zhiyu Hao
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引用次数: 0
Abstract
Angelica dahurica (AD) is both a widely used spice and a precious traditional Chinese medicine. Currently, its quality evaluation predominantly depends on traditional identification methods and physicochemical assessments, which are often subjective or time-consuming, thus limiting their suitability for rapid, non-destructive, and accurate quality evaluation. Therefore, this study constructed a quality evaluation system based on key criteria: shape, color, odour and texture. Experienced traditional medicine experts scored 611 samples according to this system, categorizing them into three quality grades. Imperatorin and isoimperatorin in 30 randomly selected batches were quantified by HPLC, revealing a positive correlation with quality grade and confirming the system's accuracy and reliability. Moreover, quality grading models were established by integrating multispectral imaging technology with artificial intelligence technologies such as CNN and Transformer. The Transformer model achieved the highest accuracy of 88.71 %. Overall, this study improves the objectivity and reproducibility of traditional identification methods. It also demonstrates that integrating artificial intelligence with multispectral imaging enables non-destructive, rapid, and precise classification of AD, offering a novel approach for quality control of medicinal materials.
期刊介绍:
Chemometrics and Intelligent Laboratory Systems publishes original research papers, short communications, reviews, tutorials and Original Software Publications reporting on development of novel statistical, mathematical, or computer techniques in Chemistry and related disciplines.
Chemometrics is the chemical discipline that uses mathematical and statistical methods to design or select optimal procedures and experiments, and to provide maximum chemical information by analysing chemical data.
The journal deals with the following topics:
1) Development of new statistical, mathematical and chemometrical methods for Chemistry and related fields (Environmental Chemistry, Biochemistry, Toxicology, System Biology, -Omics, etc.)
2) Novel applications of chemometrics to all branches of Chemistry and related fields (typical domains of interest are: process data analysis, experimental design, data mining, signal processing, supervised modelling, decision making, robust statistics, mixture analysis, multivariate calibration etc.) Routine applications of established chemometrical techniques will not be considered.
3) Development of new software that provides novel tools or truly advances the use of chemometrical methods.
4) Well characterized data sets to test performance for the new methods and software.
The journal complies with International Committee of Medical Journal Editors'' Uniform requirements for manuscripts.