Seven cases of robot-assisted radical cystectomy with Bordeaux neobladder: A clinical observation.

Bladder (San Francisco, Calif.) Pub Date : 2025-08-27 eCollection Date: 2025-01-01 DOI:10.14440/bladder.0049
Hua Yang, Xuchang Liu, Bo Wu, Jingjing Li, Yangjie Gao, Guochen Zhao, Wenjie Yang, Junyuan Bing, Xiaoming Cao
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Abstract

Background: Bladder cancer (BCa) poses a significant global health burden with mounting incidence and mortality rates. Effective treatment strategies are urgently needed to alleviate the disease burden and improve patients' quality of life (QoL).

Objective: This study aimed to evaluate the efficacy of robot-assisted radical cystectomy (RARC) plus the Bordeaux robotic intracorporeal orthotopic neobladder (riONB) technique for the treatment of BCa.

Methods: We retrospectively analyzed clinical data from seven male patients who had undergone RARC with Bordeaux riONB between June 2023 and November 2024. The median age was 68 years, and the median body mass index was 24.2 kg/m2. The study assessed their demographic data, intra- and post-operative parameters, pathological characteristics, and complications.

Results: The median operation time lasted for 583 min, with a median estimated blood loss of 375 mL and a median post-operative hospital stay of 10 days. Pathological results showed that five patients (71.4%) were at stage ≥T2. According to the Clavien-Dindo classification, six patients (85.7%) had grade I - II complications. At 6 months post-surgery, the average maximum cystometric capacity measured 397 mL, the average post-void residual urine volume was 29 mL, the average urine flow rate was 5.6 mL/s, and the incontinence-QoL score was 85. Daytime urinary control was good in five patients (71.4%), and nighttime control was good in three patients (42.9%).

Conclusion: The results indicate that RARC + Bordeaux riONB is a safe and effective surgical option for BCa, accomplishing good patient recovery and significant clinical efficacy. However, the study was subject to limitations of a small sample size and a short follow-up period. Further research with larger cohorts and longer follow-up is warranted to confirm these findings.

Abstract Image

Abstract Image

机器人辅助波尔多新膀胱根治性切除术7例临床观察。
背景:膀胱癌(BCa)的发病率和死亡率不断上升,构成了重大的全球健康负担。迫切需要有效的治疗策略来减轻疾病负担,提高患者的生活质量。目的:本研究旨在评价机器人辅助根治性膀胱切除术(RARC)联合波尔多机器人体内原位新膀胱(riONB)技术治疗BCa的疗效。方法:回顾性分析2023年6月至2024年11月期间接受Bordeaux riONB RARC治疗的7例男性患者的临床资料。中位年龄为68岁,中位体重指数为24.2 kg/m2。该研究评估了他们的人口统计学数据、术中及术后参数、病理特征和并发症。结果:中位手术时间583 min,中位估计失血量375 mL,中位术后住院时间10 d。病理结果显示5例患者(71.4%)处于≥T2期。根据Clavien-Dindo分级,6例患者(85.7%)出现I - II级并发症。术后6个月,平均最大膀胱容量397 mL,平均空后残尿量29 mL,平均尿流率5.6 mL/s,尿失禁-生活质量评分85分。5例患者白天尿控制良好(71.4%),3例患者夜间尿控制良好(42.9%)。结论:RARC + Bordeaux riONB是一种安全有效的BCa手术选择,患者恢复良好,临床疗效显著。然而,该研究受到样本量小、随访时间短的限制。进一步的研究需要更大的队列和更长时间的随访来证实这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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