[Biospecific analytical chromatography of glycopeptide antibiotics of the vancomycin group].

Abstract

An affinity sorbent was synthesized on the basis of aminoethyl cellulose and dipeptide of the D-Ala-D-Ala-OH fragment of growing peptidoglycan of the bacterial cell wall. It was shown that the sorbent had highly selective affinity to antibiotics of the vancomycin group and their biologically active derivatives and provided their biospecific chromatography.