The role of insulin and octopamine in regulating energy homeostasis and locomotion in insects

IF 5.5 1区农林科学 Q1 BIOLOGY

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-11-04 DOI:10.1016/j.cois.2025.101457

Rituja S Bisen, Sander Liessem, Martina Held, Jan M Ache

引用次数: 0

Abstract

Maintaining energy homeostasis is a fundamental requirement for survival. At the core, animals must balance periods of food-searching and feeding with other essential, energy-consuming behaviors. This also applies to insects, which spend a considerable fraction of their lifetime foraging — sometimes under extreme conditions. The motivation to search for food is increased by a lack of energy stores, which drives a hunger signal generated by the interplay between the depletion of energy stores, enteroceptors, and neuroendocrine signaling pathways. These changes alter the internal state of the animal, which modulates the activity of sensorimotor circuits to drive behavioral changes. Here, we review recent insights into the modulation of locomotor activity and foraging by two systems that play critical and antagonistic roles in linking energy homeostasis to behavioral changes in insects and other animals: the insulin and the octopamine system.

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胰岛素和章鱼胺在调节昆虫能量稳态和运动中的作用。

维持能量稳态是生存的基本要求。从本质上讲，动物必须在寻找食物和进食的过程中，与其他必要的、消耗能量的行为保持平衡。这也适用于昆虫，它们一生中相当大一部分时间都在觅食——有时是在极端条件下。寻找食物的动机会因为能量储备的缺乏而增加，而能量储备的消耗、肠感受器和神经内分泌信号通路之间的相互作用会产生饥饿信号。这些变化改变了动物的内部状态，从而调节感觉运动回路的活动来驱动行为变化。在这里，我们回顾了最近关于昆虫和其他动物的两个系统对运动活动和觅食的调节的见解，这两个系统在将能量稳态与行为变化联系起来方面起着关键和拮抗作用：胰岛素和章鱼胺系统。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current opinion in insect science BIOLOGYECOLOGYENTOMOLOGY-ECOLOGY

CiteScore

10.40

自引率

1.90%

发文量

113

期刊介绍： Current Opinion in Insect Science is a new systematic review journal that aims to provide specialists with a unique and educational platform to keep up–to–date with the expanding volume of information published in the field of Insect Science. As this is such a broad discipline, we have determined themed sections each of which is reviewed once a year. The following 11 areas are covered by Current Opinion in Insect Science. -Ecology -Insect genomics -Global Change Biology -Molecular Physiology (Including Immunity) -Pests and Resistance -Parasites, Parasitoids and Biological Control -Behavioural Ecology -Development and Regulation -Social Insects -Neuroscience -Vectors and Medical and Veterinary Entomology There is also a section that changes every year to reflect hot topics in the field. Section Editors, who are major authorities in their area, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasized. Section Editors commission articles from leading scientists on each topic that they have selected and the commissioned authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.