Ideal Cardiovascular Health in Colorectal Cancer Patients at Diagnosis

IF 2.7 3区 医学 Q2 ONCOLOGY
Clinical colorectal cancer Pub Date : 2026-03-01 Epub Date: 2025-10-12 DOI:10.1016/j.clcc.2025.10.001
María Romero-Elías , Alejandro Álvarez-Bustos , Lourdes Gutierrez , Antonio Sánchez Ruiz , Marta Méndez-Otero , Carmen Fiuza-Luces , Ana Ruiz-Casado
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引用次数: 0

Abstract

Introduction

Cardiovascular disease (CVD) and cancer are the leading causes of chronic illness and mortality in Western societies. Colorectal cancer (CRC) is the third most prevalent cancer and shares some risk factors with CVD, which is the major cause of mortality in CRC survivors. The American Heart Association recommends Life's Simple 7 to define and measure ideal cardiovascular health (iCVH). This study aimed to detail the iCVH in CRC patients at diagnosis.

Methods

A cross-sectional study of a cohort of Spanish patients with CRC describes health and behavioral factors at diagnosis. Physical activity was monitored using accelerometers; Diet was assessed through adherence to Mediterranean diet, and anthropometry was assessed by the body mass index (BMI). Hypertension, diabetes, hypercholesterolemia, and smoking were collected from clinical records.

Results

Two hundred thirty-eight CRC patients participated (66.4% male, 64.7 years mean age), 153 (64.3%) had localized disease, and 85 (35.7%) had metastatic disease. 10% had a history of CVD. 10 patients (4.3%) met 7 components of iCVH. Non-smoking (89.5%) was the most prevalent healthy behaviour, whereas BMI < 25 was the least (39.1%). Hypertension (62%) was the most common risk factor.

Conclusions

There is still some room for decreasing the habit of smoking. Initiatives for keeping a healthy diet and body composition are needed during and after the treatment.

Implications for Practice

Assessing iCVH at diagnosis, which is considered a teachable moment, would raise awareness among health practitioners and patients about the importance of cardiovascular health along CRC trajectory and about behaviours that can be improved and impact on both cardiovascular and cancer outcomes.
结直肠癌患者诊断时的理想心血管健康状况
简介:心血管疾病(CVD)和癌症是西方社会慢性疾病和死亡的主要原因。结直肠癌(CRC)是第三大流行的癌症,与心血管疾病有一些共同的危险因素,心血管疾病是结直肠癌幸存者死亡的主要原因。美国心脏协会推荐生活简单7来定义和衡量理想的心血管健康(iCVH)。本研究旨在详细介绍结直肠癌患者诊断时的iCVH。方法:一项对西班牙CRC患者队列的横断面研究描述了诊断时的健康和行为因素。使用加速度计监测身体活动;通过对地中海饮食的依从性来评估饮食,并通过体重指数(BMI)来评估人体测量。从临床记录中收集高血压、糖尿病、高胆固醇血症和吸烟。结果:238例CRC患者(男性66.4%,平均年龄64.7岁),153例(64.3%)有局限性疾病,85例(35.7%)有转移性疾病。10%有心血管疾病病史。10例患者(4.3%)满足7项iCVH指标。不吸烟(89.5%)是最普遍的健康行为,而BMI < 25最少(39.1%)。高血压(62%)是最常见的危险因素。结论:减少吸烟习惯仍有一定的空间。在治疗期间和治疗后,需要采取措施保持健康的饮食和身体成分。对实践的影响:在诊断时评估iCVH,这被认为是一个可教育的时刻,将提高卫生从业人员和患者对CRC轨迹中心血管健康重要性的认识,以及可改善的行为和对心血管和癌症结局的影响。
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来源期刊
Clinical colorectal cancer
Clinical colorectal cancer 医学-肿瘤学
CiteScore
5.50
自引率
2.90%
发文量
64
审稿时长
27 days
期刊介绍: Clinical Colorectal Cancer is a peer-reviewed, quarterly journal that publishes original articles describing various aspects of clinical and translational research of gastrointestinal cancers. Clinical Colorectal Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of colorectal, pancreatic, liver, and other gastrointestinal cancers. The main emphasis is on recent scientific developments in all areas related to gastrointestinal cancers. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.
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