María Romero-Elías , Alejandro Álvarez-Bustos , Lourdes Gutierrez , Antonio Sánchez Ruiz , Marta Méndez-Otero , Carmen Fiuza-Luces , Ana Ruiz-Casado
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引用次数: 0
Abstract
Introduction
Cardiovascular disease (CVD) and cancer are the leading causes of chronic illness and mortality in Western societies. Colorectal cancer (CRC) is the third most prevalent cancer and shares some risk factors with CVD, which is the major cause of mortality in CRC survivors. The American Heart Association recommends Life's Simple 7 to define and measure ideal cardiovascular health (iCVH). This study aimed to detail the iCVH in CRC patients at diagnosis.
Methods
A cross-sectional study of a cohort of Spanish patients with CRC describes health and behavioral factors at diagnosis. Physical activity was monitored using accelerometers; Diet was assessed through adherence to Mediterranean diet, and anthropometry was assessed by the body mass index (BMI). Hypertension, diabetes, hypercholesterolemia, and smoking were collected from clinical records.
Results
Two hundred thirty-eight CRC patients participated (66.4% male, 64.7 years mean age), 153 (64.3%) had localized disease, and 85 (35.7%) had metastatic disease. 10% had a history of CVD. 10 patients (4.3%) met 7 components of iCVH. Non-smoking (89.5%) was the most prevalent healthy behaviour, whereas BMI < 25 was the least (39.1%). Hypertension (62%) was the most common risk factor.
Conclusions
There is still some room for decreasing the habit of smoking. Initiatives for keeping a healthy diet and body composition are needed during and after the treatment.
Implications for Practice
Assessing iCVH at diagnosis, which is considered a teachable moment, would raise awareness among health practitioners and patients about the importance of cardiovascular health along CRC trajectory and about behaviours that can be improved and impact on both cardiovascular and cancer outcomes.
期刊介绍:
Clinical Colorectal Cancer is a peer-reviewed, quarterly journal that publishes original articles describing various aspects of clinical and translational research of gastrointestinal cancers. Clinical Colorectal Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of colorectal, pancreatic, liver, and other gastrointestinal cancers. The main emphasis is on recent scientific developments in all areas related to gastrointestinal cancers. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.