Occupational anaphylaxis: a comprehensive review.

IF 2.8 4区医学 Q2 ALLERGY

Current Opinion in Allergy and Clinical Immunology Pub Date : 2026-04-01 Epub Date: 2025-10-01 DOI:10.1097/ACI.0000000000001116

Regina Treudler

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引用次数: 0

Abstract

Purpose of review: Occupational anaphylaxis refers to anaphylactic reactions triggered by substances encountered in the workplace. Management of occupational anaphylaxis includes emergency treatment, substitution of elicitors (triggers), technical and organizational measures as well as personal safety precautions. This review aims to provide a current overview on the development of the field with regard to definition of occupational anaphylaxis, risk factors, elicitors, clinical manifestations, diagnosis and management.

Recent findings: Recent data from the Network for Online Registration of Anaphylaxis showed that 3.8% of cases were work-related. The vast majority of reported occupational anaphylaxis cases are caused by Hymenoptera venom followed by food allergens. Overall, occupational anaphylaxis is reported only rarely. Recently, an expert recommendation was published for defining diagnostic criteria for occupational anaphylaxis. These criteria consider if a worker was sensitized from work exposures and reacts at work or outside the workplace, or if sensitization is due to private exposure and reaction occurs at the workplace. Also, recent expert discussions of diagnosis, grading and management of anaphylaxis are presented.

Summary: Occupational anaphylaxis seems to be rare, but underreporting and underdiagnosis due to lack of awareness and due to accepted diagnostic criteria is suspected.

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职业性过敏反应：全面回顾。

审查目的：职业过敏反应是指工作场所遇到的物质引发的过敏反应。职业性过敏反应的管理包括紧急治疗、替代诱发者（触发者）、技术和组织措施以及个人安全预防措施。本文综述了职业性过敏反应的定义、危险因素、诱发因素、临床表现、诊断和管理等方面的研究进展。最近的发现：来自过敏反应在线注册网络的最新数据显示，3.8%的病例与工作有关。绝大多数报告的职业性过敏反应病例是由膜翅目毒液引起的，其次是食物过敏原。总的来说，职业性过敏反应的报道很少。最近，发表了一项专家建议，以确定职业性过敏反应的诊断标准。这些标准考虑工人是否因工作接触而致敏并在工作场所或工作场所外发生反应，或者致敏是否由于私人接触而在工作场所发生反应。此外，最近的专家讨论的诊断，分级和管理的过敏反应提出。摘要：职业性过敏反应似乎很少见，但由于缺乏意识和公认的诊断标准，可能存在漏报和漏诊的情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Allergy and Clinical Immunology 医学-过敏

CiteScore

5.90

自引率

3.60%

发文量

109

审稿时长

6-12 weeks

期刊介绍： This reader-friendly, bimonthly resource provides a powerful, broad-based perspective on the most important advances from throughout the world literature. Featuring renowned guest editors and focusing exclusively on one to three topics, every issue of Current Opinion in Allergy and Clinical Immunology delivers unvarnished, expert assessments of developments from the previous year. Insightful editorials and on-the-mark invited reviews cover key subjects such as upper airway disease; mechanisms of allergy and adult asthma; paediatric asthma and development of atopy; food and drug allergies; and immunotherapy.