History and current developments of RERF dosimetry.

IF 3.8 3区 医学 Q2 ONCOLOGY
Harry M Cullings, Sachiyo Funamoto, Stephen D Egbert, Keith T Griffin, Colin J Paulbeck, Sean J Domal, Camilo M Correa-Alfonso, Shota Shimizu, Tatsuhiko Sato, Choonsik Lee, Akira Endo, Wesley E Bolch
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引用次数: 0

Abstract

Studies of the health effects among Japanese atomic bomb survivors, including radiation-induced carcinogenesis, necessitate accurate radiation dose estimates for individual survivors from the Hiroshima and Nagasaki bombings. Efforts toward this goal commenced shortly after the bombings in 1945, resulting in a series of dosimetry systems developed over the years to calculate survivor doses for a roster currently numbering 135 852 survivors. These systems estimate a survivor's dose based on data such as the survivor's location and shielding by structures such as houses. This paper focuses on a series of systems created over the years, first by US groups and later by binational US-Japan groups, with particular emphasis on the most recent dosimetry systems: Dosimetry System 2002 and DS02 Revision 1. Furthermore, we discuss the latest advancement, the J45 phantoms, which introduces a new system of anthropomorphic phantoms for calculations of dose to specific organs of the human body with consideration of body self-shielding and has been in development over the last few years.

Abstract Image

Abstract Image

Abstract Image

反辐射剂量学的历史和当前发展。
研究日本原子弹爆炸幸存者的健康影响,包括辐射诱发的致癌作用,需要对广岛和长崎原子弹爆炸的个别幸存者进行准确的辐射剂量估计。在1945年原子弹爆炸后不久就开始了实现这一目标的努力,多年来开发了一系列剂量测定系统,用于计算目前共有135852名幸存者的幸存者剂量。这些系统根据幸存者的位置和房屋等建筑物的遮挡等数据估计幸存者的剂量。本文重点介绍了多年来由美国小组和后来由美日两国小组创建的一系列系统,特别强调了最新的剂量学系统:剂量学系统2002和DS02修订1。此外,我们讨论了最新的进展,J45幻影,它引入了一种新的拟人化幻影系统,用于计算人体特定器官的剂量,并考虑到身体的自我屏蔽,并且在过去几年中一直在发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Carcinogenesis
Carcinogenesis 医学-肿瘤学
CiteScore
9.20
自引率
2.10%
发文量
95
审稿时长
1 months
期刊介绍: Carcinogenesis: Integrative Cancer Research is a multi-disciplinary journal that brings together all the varied aspects of research that will ultimately lead to the prevention of cancer in man. The journal publishes papers that warrant prompt publication in the areas of Biology, Genetics and Epigenetics (including the processes of promotion, progression, signal transduction, apoptosis, genomic instability, growth factors, cell and molecular biology, mutation, DNA repair, genetics, etc.), Cancer Biomarkers and Molecular Epidemiology (including genetic predisposition to cancer, and epidemiology), Inflammation, Microenvironment and Prevention (including molecular dosimetry, chemoprevention, nutrition and cancer, etc.), and Carcinogenesis (including oncogenes and tumor suppressor genes in carcinogenesis, therapy resistance of solid tumors, cancer mouse models, apoptosis and senescence, novel therapeutic targets and cancer drugs).
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