Harry M Cullings, Sachiyo Funamoto, Stephen D Egbert, Keith T Griffin, Colin J Paulbeck, Sean J Domal, Camilo M Correa-Alfonso, Shota Shimizu, Tatsuhiko Sato, Choonsik Lee, Akira Endo, Wesley E Bolch
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引用次数: 0
Abstract
Studies of the health effects among Japanese atomic bomb survivors, including radiation-induced carcinogenesis, necessitate accurate radiation dose estimates for individual survivors from the Hiroshima and Nagasaki bombings. Efforts toward this goal commenced shortly after the bombings in 1945, resulting in a series of dosimetry systems developed over the years to calculate survivor doses for a roster currently numbering 135 852 survivors. These systems estimate a survivor's dose based on data such as the survivor's location and shielding by structures such as houses. This paper focuses on a series of systems created over the years, first by US groups and later by binational US-Japan groups, with particular emphasis on the most recent dosimetry systems: Dosimetry System 2002 and DS02 Revision 1. Furthermore, we discuss the latest advancement, the J45 phantoms, which introduces a new system of anthropomorphic phantoms for calculations of dose to specific organs of the human body with consideration of body self-shielding and has been in development over the last few years.
期刊介绍:
Carcinogenesis: Integrative Cancer Research is a multi-disciplinary journal that brings together all the varied aspects of research that will ultimately lead to the prevention of cancer in man. The journal publishes papers that warrant prompt publication in the areas of Biology, Genetics and Epigenetics (including the processes of promotion, progression, signal transduction, apoptosis, genomic instability, growth factors, cell and molecular biology, mutation, DNA repair, genetics, etc.), Cancer Biomarkers and Molecular Epidemiology (including genetic predisposition to cancer, and epidemiology), Inflammation, Microenvironment and Prevention (including molecular dosimetry, chemoprevention, nutrition and cancer, etc.), and Carcinogenesis (including oncogenes and tumor suppressor genes in carcinogenesis, therapy resistance of solid tumors, cancer mouse models, apoptosis and senescence, novel therapeutic targets and cancer drugs).