Behçet's syndrome: one year in review 2025.

Abstract

Behçet's syndrome (BS) is a variable-vessel vasculitis with multiorgan involvement and heterogeneous clinical manifestations. A list of studies were published on BS last year including studies that explore the epidemiology of BS in different parts of the world, role of potential immunological biomarkers in major organ involvement phenotypes, genome wide association studies, studies on micro RNAs, toll like receptors, neutrophil function and epigenetics that added to our understanding of the pathogenesis, studies on imaging and clinical findings that aim to improve diagnosis, differential diagnosis, and monitoring of each organ involvement, as well as studies on management, especially focusing on the role of TNF inhibitors compared to conventional immunosuppressives. The aim of this review is to provide a critical digest of the studies on BS published during 2024.