Interactions between Poisons, Patients, and Extracorporeal Blood Purification Therapies: A Comprehensive Analysis.

IF 2.2 3区 医学 Q3 HEMATOLOGY
Blood Purification Pub Date : 2026-01-01 Epub Date: 2025-10-21 DOI:10.1159/000549094
Matteo Pernazza, Gianluca Castellani, Matteo Marrocu, Elena Costantini, Giuseppe Gigliotti, Gianluca Villa
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引用次数: 0

Abstract

Background: Poisonings can harm through their direct effect or determining organ dysfunction. Extracorporeal blood purification therapies (EBPT) have been used for decades in case of poisonings. Although poisoning remains a major public health issue, focusing on organ dysfunction rather than the poison itself has significantly reduced mortality rates.

Summary: This review explores the complex and dynamic interactions among poisons, patients, and EBPT and describes specific poisonings where EBPT may be indicated.

Key messages: EBPT are indicated in many cases of intoxication, either to enhance clearance or for organ support. A thorough understanding of the interactions between poisons, patients, and EBPT is mandatory for proper management of each specific intoxication.

毒物、患者和体外血液净化疗法之间的相互作用:一项综合分析。
中毒可通过其直接影响或决定器官功能障碍造成伤害;几十年来,体外血液净化疗法一直用于治疗中毒。虽然中毒仍然是一个重大的公共卫生问题,但把重点放在器官功能障碍而不是毒药本身,已经大大降低了死亡率。这篇综述探讨了毒物、患者和EBPT之间复杂和动态的相互作用,并描述了EBPT可能适用的特定中毒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Blood Purification
Blood Purification 医学-泌尿学与肾脏学
CiteScore
5.80
自引率
3.30%
发文量
69
审稿时长
6-12 weeks
期刊介绍: Practical information on hemodialysis, hemofiltration, peritoneal dialysis and apheresis is featured in this journal. Recognizing the critical importance of equipment and procedures, particular emphasis has been placed on reports, drawn from a wide range of fields, describing technical advances and improvements in methodology. Papers reflect the search for cost-effective solutions which increase not only patient survival but also patient comfort and disease improvement through prevention or correction of undesirable effects. Advances in vascular access and blood anticoagulation, problems associated with exposure of blood to foreign surfaces and acute-care nephrology, including continuous therapies, also receive attention. Nephrologists, internists, intensivists and hospital staff involved in dialysis, apheresis and immunoadsorption for acute and chronic solid organ failure will find this journal useful and informative. ''Blood Purification'' also serves as a platform for multidisciplinary experiences involving nephrologists, cardiologists and critical care physicians in order to expand the level of interaction between different disciplines and specialities.
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