Prospective Evaluation of the Effectiveness of Brachial Plexus Nerve Block During the Perioperative Period in Long-Term Opioid Users Undergoing Upper Extremity Surgery - A Case Series.

IF 1.8 Q3 ANESTHESIOLOGY

Local and Regional Anesthesia Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI:10.2147/LRA.S541354

Daniel Huettner, Yue Qiu, Bedda L Rosario, Steven Orebaugh

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Abstract

Purpose: This study examined whether chronic opioid use reduces the effectiveness of brachial plexus block in patients undergoing upper extremity surgery.

Patients and methods: Patients undergoing surgery with brachial plexus blocks were divided into two groups: opioid-dependent (daily opioid use for ≥1 month) and control (no opioid use for ≥3 months). Pain scores and opioid use were recorded over 72 hours postoperatively.

Results: Forty-six patients were included (23 opioid-dependent and 23 control). The median (IQR) NRS scores upon PACU arrival were 0 (0-0) in the control group and 0 (0-5) in the opioid group (p=0.0101). The duration of the nerve block was shorter in opioid-dependent patients (14 versus 22 hours; p=0.0035).

Conclusion: Chronic opioid users experienced shorter brachial plexus block duration and more postoperative pain after being discharged home.

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长期阿片类药物使用者接受上肢手术围手术期臂丛神经阻滞疗效的前瞻性评价-一个病例系列。

目的：本研究探讨慢性阿片类药物使用是否会降低上肢手术患者臂丛阻滞的有效性。患者和方法：接受臂丛神经阻滞手术的患者分为两组：阿片类药物依赖组（每天使用阿片类药物≥1个月）和对照组（不使用阿片类药物≥3个月）。术后72小时记录疼痛评分和阿片类药物使用情况。结果：纳入46例患者（阿片类药物依赖患者23例，对照组23例）。PACU到达时，对照组的中位（IQR） NRS评分为0(0-0)，阿片类药物组为0(0-5)，差异有统计学意义（p=0.0101）。阿片类药物依赖患者的神经阻滞持续时间较短（14小时对22小时；p=0.0035）。结论：慢性阿片类药物使用者出院后臂丛神经阻滞持续时间较短，术后疼痛较多。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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