Conditional sex conversion systems for improved control of insect pests

IF 5.5 1区农林科学 Q1 BIOLOGY

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-10-18 DOI:10.1016/j.cois.2025.101454

Alexis L Kriete , Maxwell J Scott

引用次数: 0

Abstract

Conditional female-to-male sex conversion systems are promising tools for improving the Sterile Insect Technique, an environmentally-friendly form of genetic pest control. In recent years, several conditional sex conversion systems, employing various effector genes and gene expression techniques, have been designed and evaluated in diverse insect species. While no system described thus far is ready for real-world use, valuable insight into insect physiology and sex determination has been gained. Additional basic research on insect sex determination mechanisms, particularly dosage compensation, coupled with increasingly flexible and powerful tools for gene expression and editing, should enable researchers to improve existing sex conversion systems, as well as to develop new systems in non-model insect pests.

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改善害虫控制的条件性转换系统。

有条件的雌性到雄性的性别转换系统是改进昆虫不育技术（SIT）的有前途的工具，这是一种环境友好的遗传害虫控制形式。近年来，利用不同的效应基因和基因表达技术，设计并评价了几种昆虫的条件性转换系统。虽然到目前为止还没有描述的系统准备好用于现实世界，但已经获得了对昆虫生理学和性别决定的宝贵见解。对昆虫性别决定机制的进一步基础研究，特别是剂量补偿，加上越来越灵活和强大的基因表达和编辑工具，应该使研究人员能够改进现有的性别转换系统，并在非模式害虫中开发新的系统。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current opinion in insect science BIOLOGYECOLOGYENTOMOLOGY-ECOLOGY

CiteScore

10.40

自引率

1.90%

发文量

113

期刊介绍： Current Opinion in Insect Science is a new systematic review journal that aims to provide specialists with a unique and educational platform to keep up–to–date with the expanding volume of information published in the field of Insect Science. As this is such a broad discipline, we have determined themed sections each of which is reviewed once a year. The following 11 areas are covered by Current Opinion in Insect Science. -Ecology -Insect genomics -Global Change Biology -Molecular Physiology (Including Immunity) -Pests and Resistance -Parasites, Parasitoids and Biological Control -Behavioural Ecology -Development and Regulation -Social Insects -Neuroscience -Vectors and Medical and Veterinary Entomology There is also a section that changes every year to reflect hot topics in the field. Section Editors, who are major authorities in their area, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasized. Section Editors commission articles from leading scientists on each topic that they have selected and the commissioned authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.