{"title":"Left-sided clear cell renal cell carcinoma initially presenting with isolated abdominal wall metastasis: a case report.","authors":"Ji Yu, ZhongRu Sun, Qingyu Chen, Ming Yin","doi":"10.1007/s12672-025-03741-3","DOIUrl":null,"url":null,"abstract":"<p><p>Isolated abdominal wall metastasis of clear cell renal cell carcinoma is exceedingly rare. We report a case where isolated abdominal wall metastasis served as the initial manifestation while the primary renal carcinoma remained occult. The patient was admitted for a right abdominal wall mass and underwent mass excision, with postoperative pathology unexpectedly revealing metastatic clear cell carcinoma. Subsequent systematic imaging evaluation identified clear cell renal cell carcinoma in the left kidney, leading to radical left nephrectomy. This case comprehensively presents the diagnostic and therapeutic process of renal cell carcinoma with atypical site metastasis, which will enhance clinicians' ability to recognize atypical metastases of renal cell carcinoma, thereby facilitating better identification of such lesions and further guiding treatment prognosis.</p>","PeriodicalId":11148,"journal":{"name":"Discover. Oncology","volume":"16 1","pages":"1938"},"PeriodicalIF":2.9000,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12540213/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Discover. Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12672-025-03741-3","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
Abstract
Isolated abdominal wall metastasis of clear cell renal cell carcinoma is exceedingly rare. We report a case where isolated abdominal wall metastasis served as the initial manifestation while the primary renal carcinoma remained occult. The patient was admitted for a right abdominal wall mass and underwent mass excision, with postoperative pathology unexpectedly revealing metastatic clear cell carcinoma. Subsequent systematic imaging evaluation identified clear cell renal cell carcinoma in the left kidney, leading to radical left nephrectomy. This case comprehensively presents the diagnostic and therapeutic process of renal cell carcinoma with atypical site metastasis, which will enhance clinicians' ability to recognize atypical metastases of renal cell carcinoma, thereby facilitating better identification of such lesions and further guiding treatment prognosis.