Differences in advanced radiologic features of glioma subtypes under the 2021 WHO classification of tumors of the central Nervous system

IF 3.3 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology Pub Date : 2025-10-14 DOI:10.1016/j.ejrad.2025.112474

Siddhant Kumarapuram , Quirin D. Strotzer , Otto Rapalino , Rajiv Gupta

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Abstract

The 2021 World Health Organization (WHO) Classification of Tumors of the Central Nervous System (CNS) redefined glioma subtypes in the 5th edition of revised guidelines pertaining to histologic and molecular grading for CNS Tumors. Neuroradiologists’ understanding of the tumor subtypes is key to effectively assisting with diagnosis. Although it is helpful to understand the characteristics of these tumors on standard imaging modalities, including T1, T2, and FLAIR MRI Sequences, new literature reports find characteristic features of different glioma subtypes can be further enhanced with advanced imaging techniques, including ADC, SWI, MRS, and FDG-PET. In this report, we review and illustrate advanced imaging characteristics of glioma subtypes within the 2021 WHO classification. These tools will provide neuroradiologists with more data points to hypothesize brain tumor subtypes before invasive approaches are pursued.

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根据2021年WHO中枢神经系统肿瘤分类，胶质瘤亚型的晚期放射学特征差异

2021年世界卫生组织（WHO）中枢神经系统（CNS）肿瘤分类在关于中枢神经系统肿瘤的组织学和分子分级的修订指南的第5版中重新定义了胶质瘤亚型。神经放射科医师对肿瘤亚型的了解是有效协助诊断的关键。虽然在标准成像方式（包括T1、T2和FLAIR MRI序列）上了解这些肿瘤的特征是有帮助的，但新的文献报道发现，不同胶质瘤亚型的特征可以通过先进的成像技术进一步增强，包括ADC、SWI、MRS和FDG-PET。在本报告中，我们回顾并说明了2021年WHO分类中胶质瘤亚型的高级影像学特征。这些工具将为神经放射学家提供更多的数据点，以便在采取侵入性方法之前假设脑肿瘤亚型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Radiology 医学-核医学

CiteScore

6.70

自引率

3.00%

发文量

398

审稿时长

42 days

期刊介绍： European Journal of Radiology is an international journal which aims to communicate to its readers, state-of-the-art information on imaging developments in the form of high quality original research articles and timely reviews on current developments in the field. Its audience includes clinicians at all levels of training including radiology trainees, newly qualified imaging specialists and the experienced radiologist. Its aim is to inform efficient, appropriate and evidence-based imaging practice to the benefit of patients worldwide.