[Postoperative long-term complications after intestinal bypass surgery : Internal hernia, anastomotic ulcer, choledocholithiasis].

Lars Kollmann, Jakob Lauerer, Miljana Vladimirov, Christoph-Thomas Germer, Florian Seyfried
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Abstract

The most frequent long-term complications following intestinal bypass procedures that require surgical treatment are internal hernia and treatment-refractory anastomotic ulcer. The risk of internal hernia after Roux-en‑Y gastric bypass ranges from 5-15% and, although it can be reduced by meticulous intraoperative closure of mesenteric defects, it cannot be entirely prevented. Internal hernia usually becomes clinically apparent after significant postoperative weight loss, typically within months to a few years and should ideally be managed by laparoscopic repositioning of the small bowel and closure of the mesenteric defect. Treatment-refractory anastomotic ulcer is most frequently associated with risk factors such as persistent nicotine use during a Helicobacter pylori infection and discontinuation of proton pump inhibitor (PPI) treatment. In addition, anatomical features such as a large gastric pouch or a circumferentially fashioned anastomosis predispose to ulcer formation. The reported incidence after gastric bypass varies considerably and ranges between 1% and 53%. Standard management consists of rigorous elimination of risk factors combined with PPI treatment. In cases of chronicity or (covered) perforation, surgical revision with resection and reconstruction of the anastomosis is required. Choledocholithiasis secondary to cholecystolithiasis represents a particular interdisciplinary challenge due to limited endoscopic access to the papilla of Vater. Established treatment options include endoscopic balloon enteroscopy, retrograde cholangiography via the gastric remnant, which is opened laparoscopically assisted, revision of the bile duct performed during laparoscopic cholecystectomy or percutaneous transhepatic cholangial drainage (PTCD). Management of these long-term complications should preferentially be carried out in certified centers for metabolic and bariatric surgery with appropriate specific expertise.

【肠搭桥术后长期并发症:内疝、吻合口溃疡、胆总管结石】。
肠旁路手术后需要手术治疗的最常见的长期并发症是内疝和难治性吻合口溃疡。Roux-en - Y胃旁路手术后发生内疝的风险在5-15%之间,尽管术中细致地闭合肠系膜缺损可以降低发生率,但不能完全预防。腹内疝通常在术后体重显著减轻后临床表现明显,通常在几个月至几年内,理想情况下应通过腹腔镜小肠复位和肠系膜缺损闭合来治疗。难愈性吻合口溃疡最常与危险因素相关,如幽门螺杆菌感染期间持续使用尼古丁和停止质子泵抑制剂(PPI)治疗。此外,解剖特征如大胃袋或环状吻合易导致溃疡形成。胃分流术后报道的发病率差异很大,范围在1%到53%之间。标准管理包括严格消除危险因素并结合PPI治疗。在慢性穿孔或(隐蔽性)穿孔的情况下,需要手术翻修并切除和重建吻合口。继发于胆囊结石的胆总管结石是一种特殊的跨学科挑战,因为内窥镜进入Vater乳头的途径有限。已建立的治疗方案包括内镜球囊肠镜、经胃残体逆行胆管造影(腹腔镜辅助下打开)、腹腔镜胆囊切除术时胆管翻修或经皮经肝胆管引流(PTCD)。这些长期并发症的处理应优先在经过认证的代谢和减肥手术中心进行,并具有适当的专业知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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