Is vaccination a feasible public health strategy against fatal Borna disease virus 1 (BoDV-1) encephalitis? An epidemiological perspective.

IF 4.9 1区医学 Q1 MICROBIOLOGY

PLoS Pathogens Pub Date : 2025-10-13 eCollection Date: 2025-10-01 DOI:10.1371/journal.ppat.1013571

Kirsten Pörtner, Christina Frank, Hendrik Wilking, Klaus Stark, Christiane Herden, Martin Beer, Dennis Rubbenstroth, Dennis Tappe

引用次数: 0

Abstract

Human Borna disease virus 1 (BoDV-1) encephalitis is characterized by rapid clinical progression, an absence of a causal therapy and an extremely high case fatality rate. Here, we discuss prevention options through a hypothetical vaccine focusing on epidemiological features.

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疫苗接种是预防致命博尔纳病病毒1型脑炎的可行公共卫生策略吗？流行病学观点。

人博尔纳病病毒1型脑炎的特点是临床进展迅速，缺乏因果治疗，病死率极高。在这里，我们通过一种以流行病学特征为重点的假设疫苗来讨论预防方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PLoS Pathogens MICROBIOLOGY-PARASITOLOGY

自引率

3.00%

发文量

598

期刊介绍： Bacteria, fungi, parasites, prions and viruses cause a plethora of diseases that have important medical, agricultural, and economic consequences. Moreover, the study of microbes continues to provide novel insights into such fundamental processes as the molecular basis of cellular and organismal function.