Digital efforts in Spanish for enrolling Latino adults in the Brain Health Registry

IF 6.8 Q1 CLINICAL NEUROLOGY

Alzheimer''s and Dementia: Translational Research and Clinical Interventions Pub Date : 2025-10-09 DOI:10.1002/trc2.70096

Miriam T. Ashford, Anna Aaronson, Chengshi Jin, Monica R. Camacho, Joseph Eichenbaum, Aaron Ulbricht, Roxanne Alaniz, Jennefer Sorce, Sandhya Kannan, Lourdes Guerrero, David X. Marquez, Derek Flenniken, Juliet Fockler, Diana Truran, R. Scott Mackin, Monica Rivera Mindt, Alejandra Morlett Paredes, Hector M. González, Michael W. Weiner, Rachel L. Nosheny

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引用次数: 0

Abstract

INTRODUCTION

Previous culturally informed digital inclusion efforts in English effectively enrolled Latino adults into the Brain Health Registry (BHR), an online Alzheimer's disease (AD)–related registry. Because these efforts were in English only, we did not successfully reach individuals from the U.S. Latino community whose language preference is Spanish. The English-language effort had limited success enrolling Latino participants from diverse sociodemographic backgrounds (e.g., gender, education, nativity). Therefore, we tested the hypothesis that Spanish-language efforts would increase the sociodemographic diversity of enrolled Latino participants.

METHODS

The BHR is an online registry that collects longitudinal cognitive and health data. We worked in partnership with a Latino Community Science Partnership Board to develop Spanish-language, culturally informed digital inclusion efforts, including a Spanish translation of BHR, Facebook advertisements, and culturally informed recruitment websites. Here, we (1) report on the Spanish-language digital advertisement results, (2) compare the characteristics of participants enrolled through Spanish (July 2021 through June 2022) versus English (September 2020 to June 2022) advertisements, and (3) compare the characteristics of those using the BHR assessment portal in Spanish versus in English.

RESULTS

Culturally informed Spanish-language advertisements enrolled 1059 participants, including 986 who identify as Latino. Compared to participants enrolled through culturally informed English-language efforts (N = 6985), participants enrolled via Spanish-language efforts were significantly older, had less education, and had a higher percentage of male participants and those born outside the United States. Compared to participants who opted to use the BHR website in English (N = 37,199), those who opted to use the website in Spanish (n = 1088), were significantly younger, reported fewer years of education, and more frequently self-identified as male and Latino. However, these efforts failed to increase BHR task completion.

DISCUSSION

Culturally informed digital efforts in Spanish are effective at increasing sociodemographic diversity of a Latino, digital research cohort. Similar efforts can be adapted to other studies and settings to improve the generalizability of AD research.

Highlights

Implemented culturally informed, Spanish-language digital enrollment efforts.
The efforts enrolled 986 Latino individuals in 12 months.
Compared demographics of those enrolled through Spanish versus English advertising.
Spanish efforts increased enrollment of older Latino adults born outside the United States.
Efforts increased enrollment but did not increase completion of study tasks.

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在大脑健康登记处登记拉丁裔成年人的西班牙语数字努力

先前的英语文化信息数字包容工作有效地将拉丁裔成年人纳入脑健康登记处（BHR），这是一个与阿尔茨海默病（AD）相关的在线登记处。由于这些努力只使用英语，我们没有成功地接触到语言偏好为西班牙语的美国拉丁裔社区的个人。在招收来自不同社会人口背景（如性别、教育程度、出生地）的拉丁裔参与者方面，英语的努力取得了有限的成功。因此，我们检验了西班牙语学习的努力会增加登记的拉丁裔参与者的社会人口多样性的假设。方法BHR是一个收集纵向认知和健康数据的在线注册表。我们与拉丁裔社区科学伙伴关系委员会合作，开展了西班牙语的、具有文化背景的数字包容工作，包括BHR的西班牙语翻译、Facebook广告和具有文化背景的招聘网站。在这里，我们(1)报告了西班牙语数字广告的结果，(2)比较了通过西班牙语（2021年7月至2022年6月）和英语（2020年9月至2022年6月）广告招募的参与者的特征，以及(3)比较了使用西班牙语和英语BHR评估门户网站的参与者的特征。结果：西班牙语广告招募了1059名参与者，其中986名为拉丁裔。与通过了解英语文化的方式招募的参与者（N = 6985）相比，通过西班牙语方式招募的参与者年龄更大，受教育程度更低，男性参与者和出生在美国以外的参与者的比例更高。与选择使用英语BHR网站的参与者（N = 37,199）相比，选择使用西班牙语网站的参与者（N = 1088）明显更年轻，报告受教育年限更少，并且更频繁地自认为是男性和拉丁裔。然而，这些努力未能提高BHR任务的完成度。西班牙语的文化信息数字化努力在增加拉丁裔数字研究队列的社会人口多样性方面是有效的。类似的努力可以适用于其他研究和环境，以提高阿尔茨海默病研究的普遍性。实施了文化信息，西班牙语数字招生工作。这项努力在12个月内招募了986名拉丁裔人。比较通过西班牙语和英语广告注册的人口统计数据。西班牙的努力增加了在美国以外出生的老年拉丁裔成年人的入学率。努力增加了入学人数，但没有提高学习任务的完成程度。

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来源期刊

Alzheimer''s and Dementia: Translational Research and Clinical Interventions Medicine-Psychiatry and Mental Health

CiteScore

10.10

自引率

2.10%

发文量

134

审稿时长

10 weeks

期刊介绍： Alzheimer''s & Dementia: Translational Research & Clinical Interventions (TRCI) is a peer-reviewed, open access,journal from the Alzheimer''s Association®. The journal seeks to bridge the full scope of explorations between basic research on drug discovery and clinical studies, validating putative therapies for aging-related chronic brain conditions that affect cognition, motor functions, and other behavioral or clinical symptoms associated with all forms dementia and Alzheimer''s disease. The journal will publish findings from diverse domains of research and disciplines to accelerate the conversion of abstract facts into practical knowledge: specifically, to translate what is learned at the bench into bedside applications. The journal seeks to publish articles that go beyond a singular emphasis on either basic drug discovery research or clinical research. Rather, an important theme of articles will be the linkages between and among the various discrete steps in the complex continuum of therapy development. For rapid communication among a multidisciplinary research audience involving the range of therapeutic interventions, TRCI will consider only original contributions that include feature length research articles, systematic reviews, meta-analyses, brief reports, narrative reviews, commentaries, letters, perspectives, and research news that would advance wide range of interventions to ameliorate symptoms or alter the progression of chronic neurocognitive disorders such as dementia and Alzheimer''s disease. The journal will publish on topics related to medicine, geriatrics, neuroscience, neurophysiology, neurology, psychiatry, clinical psychology, bioinformatics, pharmaco-genetics, regulatory issues, health economics, pharmacoeconomics, and public health policy as these apply to preclinical and clinical research on therapeutics.