Psychopathology and the autonomic nervous system in borderline personality disorder. Part 1. The Influence of Early Adversities, Dissociation, Self-stigma, Parenting and Attachment on Disorder Severity.

IF 0.6
Neuro endocrinology letters Pub Date : 2025-09-29
Vlastimil Nesnidal, Jan Prasko, Kamila Belohradova, Jakub Vanek, Frantisek Hodny, Marie Ociskova
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Abstract

Background: Borderline Personality Disorder (BPD) is a complex psychiatric condition characterized by significant emotional instability, impulsivity, and intense interpersonal difficulties. This study examines the relationship between early traumatic experiences, attachment, dissociation, self-stigmatization, autonomic nervous system activity, specifically heart rate variability (HRV), and the severity of BPD symptoms.

Objective: To explore the associations between psychosocial and physiological factors and the severity of BPD symptoms, with a focus on early adverse experiences, adult attachment styles, HRV, and self-stigmatization.

Methods: The study sample consisted of 75 hospitalized BPD patients. HRV was measured, and self-report questionnaires were used to assess early traumas (Childhood Trauma Questionnaire), parenting style (Parental Bonding Instrument), adult attachment style (Experiences in Close Relationships Scale), and dissociation (Dissociative Experience Scale). Self-stigmatization was evaluated using the Internalized Stigma of Mental Illness (ISMI) scale, while symptom severity was assessed using self-report and clinician-administered scales, including the CGI-BPD, Beck Depression Inventory-II, and Beck Anxiety Inventory.

Results: Significant correlations were found between early traumas, attachment, and the severity of BPD symptomatology. Higher levels of emotional abuse in childhood correlated with earlier onset and greater symptom severity. HRV analysis indicated a link between sympathetic nervous system activation and specific BPD symptoms, particularly in patients with high levels of attachment anxiety. Self-stigmatization was associated with increased symptom severity and reduced treatment response.

Conclusion: The findings confirm that early traumatic experiences, adult attachment, and self-stigmatization are key factors in understanding symptom severity and emotional dysregulation in BPD. Targeted interventions addressing these areas may significantly improve treatment outcomes for BPD patients.

边缘型人格障碍的精神病理与自主神经系统。第1部分。早期逆境、分离、自我污名、父母教养和依恋对障碍严重程度的影响。
背景:边缘型人格障碍(BPD)是一种复杂的精神疾病,以显著的情绪不稳定、冲动和强烈的人际关系困难为特征。本研究探讨了早期创伤经历、依恋、分离、自我污名化、自主神经系统活动,特别是心率变异性(HRV)与BPD症状严重程度之间的关系。目的:探讨心理社会和生理因素与BPD症状严重程度的关系,重点关注早期不良经历、成人依恋类型、HRV和自我污名化。方法:研究样本为75例住院BPD患者。测量HRV,并采用自我报告问卷评估早期创伤(童年创伤问卷)、父母教养方式(父母结合量表)、成人依恋方式(亲密关系体验量表)和分离(分离体验量表)。自我污名化采用精神疾病内化污名(ISMI)量表进行评估,而症状严重程度采用自我报告和临床管理的量表进行评估,包括CGI-BPD、Beck抑郁量表- ii和Beck焦虑量表。结果:早期创伤、依恋与BPD症状严重程度之间存在显著相关性。儿童期较高程度的情绪虐待与发病时间早、症状严重程度高相关。HRV分析表明交感神经系统激活与特定BPD症状之间存在联系,特别是在高度依恋焦虑的患者中。自我污名化与症状严重程度增加和治疗反应降低有关。结论:早期创伤经历、成人依恋和自我污名化是理解BPD症状严重程度和情绪失调的关键因素。针对这些领域的针对性干预可能会显著改善BPD患者的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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