Amr Selim, Nikhil Ponugoti, Deepak Menon, Geraint Thomas
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引用次数: 0
Abstract
Background: Subtrochanteric hip fractures present a treatment challenge due to their varied etiologies, complexity, and associated complications. While intramedullary nailing is the standard treatment, the choice between short and long nails remains controversial. The aim of this meta-analysis was to compare the complication rates of short versus long cephalomedullary nail fixation in the treatment of subtrochanteric hip fractures.
Methods: A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, Medline, Embase, and CINAHL databases were searched for relevant studies up to May 2025. Inclusion criteria comprised studies directly comparing short and long nails in treating subtrochanteric fractures, including randomized controlled trials and comparative studies. Data synthesis and statistical analysis were performed using RevMan 5.23.5 software.
Results: After screening, 5 retrospective comparative studies met the inclusion criteria, encompassing a total of 4,384 subtrochanteric fracture subjects. The weighted mean age was 82 years, with women representing 70.7% of the sample. Implant failure (odds ratio [OR] 2.12; 95% confidence interval [CI] [1.15-3.92]; p = 0.02) and peri-implant fractures (OR 4.03; 95% CI [1.46-11.14]; p = 0.007) were significantly more common with short nails. The reoperation rate was higher with short nails but not statistically significant (OR 1.33; 95% CI [0.87-2.04]; p = 0.19). No significant differences were observed between groups for nonunion (OR 0.96; 95% CI [0.40-2.33]; p = 0.94), deep infection (OR 0.70; 95% CI [0.23-2.17]; p = 0.40), or 1-year mortality (OR 0.83; 95% CI [0.43-1.58]; p = 0.57).
Conclusion: The use of short nails in the management of subtrochanteric hip fractures is associated with higher rates of implant failure and peri-implant fractures, with equivalent rates of nonunion, infection, 1-year mortality, and reoperation. These findings highlight the need for a well-conducted trial to assess the overall benefits and to determine the lowest level of subtrochanteric fracture that can be safely treated with short nails.
Level of evidence: Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:髋粗隆下骨折由于其多种病因、复杂性和相关并发症,给治疗带来了挑战。虽然髓内钉是标准的治疗方法,但短钉和长钉的选择仍然存在争议。本荟萃分析的目的是比较短髓内钉与长髓内钉固定治疗股骨粗隆下骨折的并发症发生率。方法:按照系统评价和荟萃分析指南的首选报告项目进行系统评价。检索截至2025年5月的PubMed、Medline、Embase和CINAHL数据库的相关研究。纳入标准包括直接比较短钉和长钉治疗转子下骨折的研究,包括随机对照试验和比较研究。采用RevMan 5.23.5软件进行数据综合和统计分析。结果:经筛选,5项回顾性比较研究符合纳入标准,共纳入4384例粗隆下骨折患者。加权平均年龄为82岁,女性占样本的70.7%。短钉患者种植体失败(优势比[OR] 2.12; 95%可信区间[CI] [1.15-3.92]; p = 0.02)和种植体周围骨折(优势比[OR] 4.03; 95% CI [1.46-11.14]; p = 0.007)更为常见。短指甲的再手术率较高,但差异无统计学意义(OR 1.33; 95% CI [0.87-2.04]; p = 0.19)。在骨不连(OR 0.96; 95% CI [0.40-2.33]; p = 0.94)、深度感染(OR 0.70; 95% CI [0.23-2.17]; p = 0.40)和1年死亡率(OR 0.83; 95% CI [0.43-1.58]; p = 0.57)方面,两组间无显著差异。结论:短钉治疗股骨粗隆下骨折与较高的假体失败率和假体周围骨折相关,其不愈合、感染、1年死亡率和再手术率相当。这些发现强调需要进行一项良好的试验来评估总体效益,并确定可以安全使用短钉治疗的最低粗隆下骨折水平。证据等级:三级。有关证据水平的完整描述,请参见作者说明。