Teddy J. Akiki, Leanne M. Williams, Thomas Wolfers, Yanwu Yang, Daniel Stahl, Claire M. Gillan
{"title":"Transforming psychiatry with computational and brain-based methods","authors":"Teddy J. Akiki, Leanne M. Williams, Thomas Wolfers, Yanwu Yang, Daniel Stahl, Claire M. Gillan","doi":"10.1038/s43588-025-00884-9","DOIUrl":null,"url":null,"abstract":"Integrating computational methods with brain-based data presents a path to precision psychiatry by capturing individual neurobiological variation, improving diagnosis, prognosis, and personalized care. This Viewpoint highlights advances in normative and foundation models, the importance of clinically grounded principles, and the role of robust measurement and interpretability in progressing mental health care.","PeriodicalId":74246,"journal":{"name":"Nature computational science","volume":"5 10","pages":"844-847"},"PeriodicalIF":18.3000,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature computational science","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43588-025-00884-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
Integrating computational methods with brain-based data presents a path to precision psychiatry by capturing individual neurobiological variation, improving diagnosis, prognosis, and personalized care. This Viewpoint highlights advances in normative and foundation models, the importance of clinically grounded principles, and the role of robust measurement and interpretability in progressing mental health care.