Exploring Goal-Concordant Medication Use Among VA Community Living Center Residents With Dementia.

IF 4.5
Joshua D Niznik, Lena K Makaroun, Florentia E Sileanu, Nicole Beyer, Xinhua Zhao, Kelvin Tran, Keri L Rodriguez, Laura C Hanson, Thomas R Radomski, Loren J Schleiden, Alexa Ehlert, Carolyn T Thorpe
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Abstract

Background: Documentation of patient goals and preferences within medical records has the potential to align medication use with goals of care (GoC) and individualize medication appropriateness criteria. We characterized patient and surrogate-expressed GoC for older Veterans living with dementia and explored concordance with medication use during VA Community Living Center (CLC) (i.e., nursing home) stays.

Methods: We conducted a cross-sectional analysis using the VA Residential History File, Minimum Data Set, Corporate Data Warehouse, and Medicare claims for Veterans with dementia admitted to VA CLCs from 4/2021 to 12/2021 for > 7 days. We extracted free text responses for "Veteran goals in own words" from a standardized GoC note. Two coders classified GoC topics using iterative coding. We examined bar code medication administration data for aspirin, benzodiazepines, opioids and antidementia medications within the 7 days following admission. We determined a schema for potential goal-concordant medication use (e.g., opioids for GoC focused on comfort) and assessed concordance of medication use with GoC topics.

Results: Among 1000 VA CLC residents with dementia and GoC documented, 46.4% of responses were reported by the Veteran versus a surrogate. Common topics included comfort (44.6%), life-sustaining treatments (31.8%), function (13.7%), care setting/transitions (12.9%), and life prolongation (11.2%). Medications were seldom discussed. Opioid and benzodiazepine use was classified as goal-concordant for 56.7% and 72.2% of patients who used them. Aspirin and antidementia medication use was more commonly classified as goal-discordant (54.7% and 38.7%, respectively).

Conclusions: Goals elicited via an open-ended question provided only indirect information relevant to medication use, but in many cases could be used to refine judgments of appropriateness. Integration of patient goals into formal criteria evaluating medication appropriateness is a logical next step for medication optimization research. Future research should explore the utility of questions specific to medications in GoC conversations for individuals with dementia.

退伍军人事务部社区生活中心痴呆患者目标一致性药物使用的探讨。
背景:病历中患者目标和偏好的记录有可能使药物使用与护理目标(GoC)保持一致,并使药物适当性标准个性化。我们分析了老年痴呆症退伍军人患者和代体表达的GoC,并探讨了在退伍军人社区生活中心(CLC)(即养老院)期间用药的一致性。方法:我们对2021年4月至2021年12月入住VA CLCs的痴呆症退伍军人进行了横断面分析,使用了VA居住历史文件、最小数据集、企业数据仓库和医疗保险索赔。我们从标准化的GoC笔记中提取了“老兵目标”的免费文本回复。两个编码员使用迭代编码对GoC主题进行分类。我们检查了入院后7天内阿司匹林、苯二氮卓类药物、阿片类药物和抗痴呆药物的条形码给药数据。我们确定了一个潜在目标一致的药物使用模式(例如,阿片类药物用于GoC,侧重于舒适度),并评估了药物使用与GoC主题的一致性。结果:在1000名VA CLC合并痴呆和GoC的住院患者中,退伍军人报告的应答率为46.4%。常见的主题包括舒适度(44.6%)、维持生命的治疗(31.8%)、功能(13.7%)、护理环境/过渡(12.9%)和延长生命(11.2%)。很少讨论药物问题。阿片类药物和苯二氮卓类药物的使用分别为56.7%和72.2%。阿司匹林和抗痴呆药物的使用更常被归类为目标不一致(分别为54.7%和38.7%)。结论:通过开放式问题引出的目标仅提供与药物使用相关的间接信息,但在许多情况下可用于完善适当性的判断。将患者目标整合到评估药物适当性的正式标准中是药物优化研究的合乎逻辑的下一步。未来的研究应该探索在GoC对话中针对痴呆症患者的特定药物问题的效用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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