{"title":"10-(4-Chloro-phen-yl)-4-[(4-fluoro-phen-yl)amino]-5-phenyl-5,8,9,10-tetra-hydro-pyrimido[4,5-<i>b</i>]quin-olin-6(7<i>H</i>)-one.","authors":"Adesola A Adeleke, Sizwe J Zamisa, Bernard Omondi","doi":"10.1107/S2414314625007758","DOIUrl":null,"url":null,"abstract":"<p><p>The title compound, C<sub>29</sub>H<sub>22</sub>ClFN<sub>4</sub>O, crystallizes with one mol-ecule in the asymmetric unit. The pyrimidinyl and anilinyl moieties subtend a dihedral angle = 36.65 (5)°, while the di-hydro-pyridine and phenyl rings are approximately orthogonal [dihedral angles = 81.65 (7) and 89.95 (7)°]. The crystal packing reveals alternating C-H⋯π and C-F⋯π inter-actions forming corrugated two-dimensional sheets along the <i>ac</i> plane, which are further linked into a three-dimensional network through N-H⋯O and C-H⋯O hydrogen bonds and Cl⋯Cl inter-actions.</p>","PeriodicalId":94324,"journal":{"name":"IUCrData","volume":"10 Pt 9","pages":"x250775"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498024/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IUCrData","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1107/S2414314625007758","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The title compound, C29H22ClFN4O, crystallizes with one mol-ecule in the asymmetric unit. The pyrimidinyl and anilinyl moieties subtend a dihedral angle = 36.65 (5)°, while the di-hydro-pyridine and phenyl rings are approximately orthogonal [dihedral angles = 81.65 (7) and 89.95 (7)°]. The crystal packing reveals alternating C-H⋯π and C-F⋯π inter-actions forming corrugated two-dimensional sheets along the ac plane, which are further linked into a three-dimensional network through N-H⋯O and C-H⋯O hydrogen bonds and Cl⋯Cl inter-actions.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
