{"title":"Cardiac Mass, Bacteremia, and Embolic Stroke","authors":"Ngoc Thai Kieu MD , Mahmoud Elamin MD , Syed Haseeb MD , Rija Shahid MBBS , Thuy Hao Nguyen MD , Husam Katib MD , Vien T. Truong MD , Ahmed Ali MBBS , Noman Chaudhary MBBS , Thach Nguyen MD","doi":"10.1016/j.jaccas.2025.105339","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Cardiac masses may mimic tumors or vegetations. Differentiation is essential, particularly in the context of bacteremia and embolic complications.</div></div><div><h3>Case Summary</h3><div>A 75-year-old man presented with fatigue, myalgia, and new-onset atrial fibrillation. Transesophageal echocardiography revealed a mitral valve mass with features suggestive of fibroelastoma or myxoma. Blood cultures were positive for <em>Streptococcus mitis</em>. The patient subsequently developed an intracerebral hemorrhage requiring craniotomy. Serial imaging demonstrated resolution of the mitral valve mass, supporting a diagnosis of vegetation.</div></div><div><h3>Discussion</h3><div>Diagnosis of infective endocarditis requires integration of clinical context, microbiologic data, and serial imaging rather than reliance on echocardiographic appearance alone. Anticoagulation strategies must be individualized after hemorrhagic events.</div></div><div><h3>Take-Home Messages</h3><div>Cardiac masses in the setting of bacteremia require careful interpretation as lesions that appear benign may represent vegetations. Accurate diagnosis depends on integration of Duke criteria and serial transesophageal echocardiography evaluations, rather than reliance on a single echocardiogram.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 31","pages":"Article 105339"},"PeriodicalIF":0.0000,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JACC. Case reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666084925021217","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
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Abstract
Background
Cardiac masses may mimic tumors or vegetations. Differentiation is essential, particularly in the context of bacteremia and embolic complications.
Case Summary
A 75-year-old man presented with fatigue, myalgia, and new-onset atrial fibrillation. Transesophageal echocardiography revealed a mitral valve mass with features suggestive of fibroelastoma or myxoma. Blood cultures were positive for Streptococcus mitis. The patient subsequently developed an intracerebral hemorrhage requiring craniotomy. Serial imaging demonstrated resolution of the mitral valve mass, supporting a diagnosis of vegetation.
Discussion
Diagnosis of infective endocarditis requires integration of clinical context, microbiologic data, and serial imaging rather than reliance on echocardiographic appearance alone. Anticoagulation strategies must be individualized after hemorrhagic events.
Take-Home Messages
Cardiac masses in the setting of bacteremia require careful interpretation as lesions that appear benign may represent vegetations. Accurate diagnosis depends on integration of Duke criteria and serial transesophageal echocardiography evaluations, rather than reliance on a single echocardiogram.