Bringing veteran mental health promotion and suicide prevention efforts upstream: The THRiVE study protocol

IF 1.9 3区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Contemporary clinical trials Pub Date : 2025-10-04 DOI:10.1016/j.cct.2025.108100

Shannon M. Blakey , J. Russ Vandermaas-Peeler , Jennifer Counts , Julie Croxford , Kristine L. Rae Olmsted , Phil Gant , Eric B. Elbogen , Kat Asman

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引用次数: 0

Abstract

Background

Transition from military to civilian life presents both opportunities and challenges. Although existing programs provide newly separated veterans (NSVs) with career transition support, these programs do not fully address psychosocial aspects of reintegrating into civilian life. This is problematic because the military transition is a time during which NSVs are at higher risk for mental health disorders and suicide. Behavioral Activation (BA), an evidence-based psychotherapy that holds potential for optimizing psychosocial well-being during the military transition, could be adapted into an upstream mental health promotion and suicide prevention program to fill this gap. This study involves a one-arm trial to pilot test a BA-based program, called Transition Health and Resilience through Valued Experiences (THRiVE), for NSVs.

Methods

Up to 40 NSVs will receive THRiVE delivered virtually to small groups by a veteran peer facilitator. Self-report assessments will be administered at baseline, immediately post-THRiVE, and 3 months after THRiVE. Primary outcomes assess program feasibility and acceptability. Secondary outcomes explore preliminary effects on mental health symptoms, risk factors for suicidal ideation, and psychosocial functioning. Consistent with community-based participatory research models, the investigative team is partnering with a veteran Advisor and a Community Advisory Board composed of veterans and veteran spouses.

Conclusion

If successful, this trial would point toward potential means for optimizing mental health outcomes during the military transition. Positive findings would lay groundwork for testing the efficacy of THRiVE in larger and diverse samples. This study is registered in ClinicalTrials.gov (NCT06778278).

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将退伍军人心理健康促进和自杀预防工作推向上游：THRiVE研究协议。

背景：从军队到平民生活的过渡带来了机遇和挑战。尽管现有的项目为新近分离的退伍军人（nsv）提供职业过渡支持，但这些项目并没有完全解决重新融入平民生活的心理社会问题。这是有问题的，因为在军事过渡时期，nsv患精神疾病和自杀的风险更高。行为激活（BA）是一种基于证据的心理疗法，在军事转型期间具有优化心理社会健康的潜力，可以适应上游的心理健康促进和自杀预防计划，以填补这一空白。这项研究包括一项单臂试验，以试点测试一个基于ba的项目，名为“通过有价值的经验过渡健康和恢复力”（THRiVE），针对nsv。方法：多达40名nsv将接受由资深同伴促进者以虚拟方式向小组交付的THRiVE。自我报告评估将在基线进行，在茁壮成长后立即进行，在茁壮成长后3个 月进行。主要结果评估项目的可行性和可接受性。次要结局探讨对心理健康症状、自杀意念危险因素和心理社会功能的初步影响。按照基于社区的参与性研究模式，调查小组正在与退伍军人顾问和由退伍军人及其配偶组成的社区咨询委员会合作。结论：如果试验成功，该试验将为优化军事转型期间的心理健康结果提供潜在的手段。阳性结果将为在更大、更多样化的样本中测试THRiVE的功效奠定基础。该研究已在ClinicalTrials.gov注册（NCT06778278）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Contemporary clinical trials 医学-药学

CiteScore

3.70

自引率

4.50%

发文量

281

审稿时长

44 days

期刊介绍： Contemporary Clinical Trials is an international peer reviewed journal that publishes manuscripts pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from disciplines including medicine, biostatistics, epidemiology, computer science, management science, behavioural science, pharmaceutical science, and bioethics. Full-length papers and short communications not exceeding 1,500 words, as well as systemic reviews of clinical trials and methodologies will be published. Perspectives/commentaries on current issues and the impact of clinical trials on the practice of medicine and health policy are also welcome.